1. tipiX Rapid Visualization of Large Datasets Adrian V. Dalca, Ramesh Sridharan, Natalia Rost, Polina Golland 1

3. 3 Alzheimer’s Disease, Brain MRI, PET 2000+ Brain Mapping MRI, fMRI, MRA, DTI, PET ~800 Heart, Brain MRI 2500+, 6000 Stroke, Brain MRI 4000+ Autism, Brain MRI, fMRI 1000+ COPD Lung CT 10,000+

4. Outline Current methods for exploring datasets Our method: tipiX User study Conclusion 4

5. Outline Current methods for exploring datasets Our method: tipiX User study Conclusion 5

6. Current Methods: Visualize Subjects 6

7. 7

8. Current Methods: Grids 8

9. Statistics Summarize data and results Appropriate statistics are difficult to determine Provide concise, superficial overview of data Usually won’t detect patterns, imaging details 9

10. Outline Current methods for exploring datasets Our method: tipiX User study Conclusion 10

11. tipiX Demonstration 11 tipiX demonstration Dataset

12. Exploring Dimensions 12 Dataset Dimensions Spatial dimensions (2D slice) Volume Depth Subject ID Longitudinal data Temporal data (fMRI) Different scan modality Clinical Factors (e.g. Age) Parameter sweeps Trying different algorithms

13. tipiX Demo Slice vs subject number Lesion Registration Difficult registration Groups vs age Time evolution of vascular disease Slice vs parameter grid Parameter sweep Slice vs subject number Grid Original dataset exploration 13

14. White Matter Hyperintensity 14

15. Features Open source, works directly on modern browser Processing is client-side Streamlined collaboration: specific tipiX link encodes dataset Assumes collaborators have data access Many features present and in development Display volume info, volume control slice:drop binding, website embedding… Come to the demo! 15

16. Outline Current methods for exploring datasets Our method: tipiX User study Conclusion 16

17. User Study 17 ordered subjects Threshold registration quality 500 subjects … 1 500

18. Outline Current methods for exploring datasets Our method: tipiX User study Conclusion 18

19. Conclusions Visualization of large datasets across many dimensions is important tipiX presents an intuitive visualization platform Enables pattern detection, outlier detection, visualization of trends Web implementation enables easy collaboration, open-source development User study demonstrates promising ability to explore datasets quickly 19