Bacterial Meningitis By: Lauren Powell. What is Bacterial Meningitis? Inflammation of the meninges ihttp://en.wikipedia.org/wiki/Meningitis.

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Presentation transcript:

Bacterial Meningitis By: Lauren Powell

What is Bacterial Meningitis? Inflammation of the meninges ihttp://en.wikipedia.org/wiki/Meningitis

What bacteria(s) cause it? Age GroupCauses NewbornGroup B Streptococci, Escherichia coli, Listeria monocytogenes Infant Neisseria meningitidis, Haemophilus influenzae, Streptococcus pneumoniae ChildrenN. meningitidis, S. pneumoniae AdultS. pneumoniae, N. meningitidis, Mycobacteria (

Neisseria meningitidis Anti-phagocytic polysaccharide capsule Surface proteins

How N. meningitidis enters the meninges

Is bacterial meningitis contagious? Spread by respiratory or throat secretions Image:

People at High Risk Children under 5 Living in close contact Immunocompromised Severe head trauma or chronic infection Image:

Symptoms Fever, headache, stiff neck Infants: inactivity, vomiting, irritability, poor feeding Image:

How to Diagnose? Grow bacteria from cerebrospinal fluid ▫spinal tap Image:

Treatment Antibiotics ▫Cephalosporins, Penicillin-type antibiotics, & Aminoglycoside drugs Corticosteroids Prophylaxis ▫Rifampin, Cipro, & Rocephin Imagedic.academic.ru/dic.nsf/ruwiki/

Resistance THREAT! Certain strains resistant to penicillin Image:

Complications Hearing loss, learning disability, paralysis Severe cases: brain damage, coma, or death image: wwwsodahead.com/.../question /

Prevention Routine Immunization Good hygiene Image: health.org/media/images/Bacterial%20Men%20Table.gif

Developed vs. Developing Countries Developed ▫3 per 100,000 annually Developing ▫Epidemics ▫Sub-Saharan Africa: 500 per 100,000 annually

♦ "Meningitis belt" ♦ epidemic zones ♦ sporadic cases

Public Health Response (WHO) Epidemic Preparedness Epidemic Response Image:

Bibliography