Dermatophytosis Cutaneous mycosis Dermatomycosis Yeast Saprophytes Systemic mycosis Dermatophytes Dermatophytosis
Dermatophytosis Definition Greek English Persian Dermatophytes
Dermatophytosis Dermatophyte Sexual Asexual Trichophyton Microsporum Arthroderma Asexual Macroconidia Trichophyton Microsporum Epidermophyton
Dermatophytosis Trichophyton Microsporum Epidermophyton Cylinder Spindle Epidermophyton Club
Dermatophytosis Trichophyton Microsporum Epidermophyton T.rubrum, T.mentagrophytes, T.violaseum, T.schoenleinii, T.verrucosum Microsporum M.canis, M.gypseum Epidermophyton E.floccosum
Dermatophytosis Geophilic Zoophilic Anthropophilic M.gypseum M.canis, T.verrucosum Anthropophilic T.rubrum, T.violaseum, T.schoenleinii E.floccosum
Dermatophytosis Tinea capitis Tinea barbae Tinea cruris Tinea pedis Tinea mannum Tinea corporis Tinea unguium
Tinea capitis Definition Trichophyton & Microsporum Clinical manifestation Crust Krion Scatulum Age Genus Ectothrix, Endothrix, Favus
Ectothrix Outside Krion Cuticle Gray patch Age Genus After maturation M.canis, M.audouinii, T.verrucosum, T.mentagrophytes
M.canis Zoophilic Dog & cat Yellow Microconidia Few Macroconidia Thick wall Knob
M.gypseum Geophilic Favus( may be) Red Don't have knob
Endothrix Inside Cuticle Black dot, bald patch Age Genus After maturation Anthropophilic T.violaceum, T.sudanense, T.tonsuranse
Favus Hyphae (Air canal) lustreless scatulum Age Genus After maturation Cheesy or mouse judder T.schoenlinii
T.schoenleinii Anthropophilic Favic chandelier
Differential diagnosis Alopecia Trichotillomania
Laboratory diagnosis Sampling Culture Direct Sesser Scc(2) Ectothrix, Endothrix, Favus
Dermatophytosis Tinea capitis
Dermatophytosis Tinea capitis
Dermatophytosis Tinea capitis
Dermatophytosis Tinea capitis
Dermatophytosis Tinea capitis
Dermatophytosis Tinea capitis
Dermatophytosis Tinea capitis
Dermatophytosis Tinea capitis
Dermatophytosis Tinea capitis
Dermatophytosis Tinea capitis
Dermatophytosis Tinea capitis
Dermatophytosis Tinea capitis
Dermatophytosis Tinea capitis
Dermatophytosis Tinea capitis
Tinea barbae Definition Genus Age Beard & mustache Zoophilic T.verrucosum, T.mentagrophytes
T.Verrucosum Zoophilic Cow & cattle 37° Chlamydioconidia
Tinea barbae Clinical manifestation Circular Scaling Vesicle Ectothrix, Endothrix, Favus
Dermatophytosis Tinea barbae
Dermatophytosis Tinea barbae
Dermatophytosis Tinea barbae
Tinea barbae Differential diagnosis Alopecia Laboratory diagnosis
Tinea cruris Definition Sever itch With tinea pedis Ecology Male Anthropophilic E.floccosum, T.mentagrophytes, T.rubrum
E.floccosum Anthropophilic Do not have microconidia Macroconidia 2-4 or 3-5 cells E.stoackdaleae
Tinea cruris Clinical manifestation Maculae Red Vesicle Erythematic Itch Don't involve pubis
Dermatophytosis Tinea cruris
Dermatophytosis Tinea cruris
Dermatophytosis Tinea cruris
Dermatophytosis Tinea cruris
Tinea pedis Athlet ́s foot Age Shoes, warm, moisture T.M, T.R, E.F
Tinea pedis Clinical manifestation Chronic intertrigenous Chronic papulosquamous hyperkeratotic Vesicular or sub acute Acute ulcerative
Tinea pedis Chronic intertrigenous Common type White scale Between 5,4 & 4,3 Itch
Dermatophytosis Tinea pedis
Dermatophytosis Tinea pedis
Dermatophytosis Tinea pedis
Tinea pedis Chronic papulosquamous hyperkeratotic T.rubrum Moccasin foot Scaling
Dermatophytosis Tinea pedis
Dermatophytosis Tinea pedis
Tinea pedis Vesicular or sub acute T.M, T.R Id reaction Dermatophytid
Dermatophytosis Tinea pedis
Dermatophytosis Tinea pedis
Dermatophytosis Tinea pedis
Dermatophytosis Tinea pedis
Dermatophytosis Tinea pedis
Tinea pedis Acute ulcerative Bacteria Treatment is difficult
Tinea mannum Definition Position Clinical manifestation Agents
T.mentagrophytes 4 strain Interdigital is anthropophilic Erinaci is zoophilic (-) Hair penetration DW 20 ml 10% yeast extract 5D Horse hair 25° to 4 week
T.mentagrophytes Hyphae Spiral or coil Macroconidia Club
T.rubrum Anthropopilic CMA + Urease - Hair - Sorbitol +
Tinea corporis Definition Trichophyton Microsporum Body reaction Contagious Direct & indirect Annular Center & margin Vesicle T.M, T.V
Dermatophytosis Tinea corporis
Dermatophytosis Tinea corporis
Dermatophytosis Tinea corporis
Tinea corporis Tinea imbricata T.concentricum Anthropophilic Clinical manifestation Genetic Ecology
Tinea imbricata
Tinea imbricata
Laboratory diagnosis Tinea cruris, pedis, mannum & corporis Sampling Direct Culture
Tinea unguium Definition Onychomycosis Yeast Saprophytes scopulariopsis
Tinea unguium Leukonychia mycotica invasive
Dermatophytosis Tinea unguium
Dermatophytosis Tinea unguium
Dermatophytosis Tinea unguium
Dermatophytosis Tinea unguium
Dermatophytosis Tinea unguium
Dermatophytosis Tinea unguium
Dermatophytosis Tinea unguium
Dermatophytosis Onychomycosis
Dermatophytosis Onychomycosis
Dermatophytosis Treatment Griseofulvine Terbinafin
Factors involved Regional Individual Heat Humidity Local Systemic Hyperhydrosis Local steroid Systemic Immunosuppression Corticosteroid
Antigens Complex structure Cell wall Antigen Enzymes
Cell wall Antigen Chitin Glucan Mannoprotein Galactomannan
Enzymes Keratinase Elastase Collagenase Proteinase Metalloproteinase Serine proteinase
Immune system Skin Unsaturated transferin α2 macroglobulin
Skin Physical & chemical barrier Innate immunity Low humidity UV Flora
skin Keratinization & Epidermal Proliferation Antifungal agent Increase turn over Shedding Antifungal agent Saturated fatty acid
Immune system Unsaturated transferin α2 macroglobulin Free iron e chain transport Krebs cycle α2 macroglobulin Keratinase inhibition
The inflammatory response Reverse relationship Inflammatory & chronic Anthropophilic Inflammation low Infection permanent Zoophilic & geophilic Inflammation sever Infection self limitation
The inflammatory response Dermatophyte → complement → chemo tactic alternative C5a Neutrophile Activation Myeloproxidase Oxidative Hydrogen peroxide Super oxide Defensin Nonoxidative Catepsin Lactoferin
Humeral immunity Types of Ab IgG, IgM, IgA & IgE Nonprotective
Cell mediated immunity Deficiency in CMI Permanent infection Recurrent infection
Regulation Of Immune Response Mannan Immune inhibitor Blocking of monocyte receptors In vitro Inhibition of lymphoblast production Inhibition of lymphocyte proliferation
Immunization T.verrucosum LFT-130 Drug therapy