National Children’s Study University of New Mexico HSC & Valencia County Partnership 3X5X5 Signature Program in Child Health –July 15, 2008 Robert D Annett.

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Presentation transcript:

National Children’s Study University of New Mexico HSC & Valencia County Partnership 3X5X5 Signature Program in Child Health –July 15, 2008 Robert D Annett PhD, Principal Investigator Co-Investigators: Sally Davis PhD Renate Savich MD Beth Tigges PhD Kristine Tollestrup PhD Andy Rowland PhD

What will the NCS Mean to Our Children? Identification of environmental factors which contribute to health, development and behavior problems Prematurity, asthma, diabetes, injury, obesity, neurobehavioral development (e.g., ADHD, autism) Improve understanding of the biology and genetics of health, development, and behavior Provide evidence-based information on which to base decisions about practice and policy Economic benefit 12.5% reduction in obesity/DM  $14.5 billion potential savings 8% reduction in learning problems  $100 billion potential savings Provide database for future pediatric research

Overview of Study Procedures Recruit from preconception or early pregnancy Minimum of 16 home and clinic-based visits (preconception through age 21) Contact by telephone, computerized or mail-in questionnaires up to every 3 months until 5 years of age; annually thereafter Screening18 months (Home) Preconception3 years (Clinic) 1 st Trimester (Home) 5 years (Clinic) 2 nd Trimester (Clinic) 7 years (Home) 3 rd Trimester (Clinic) 9 years (Clinic) Delivery12 years (Clinic) 1 month (Home)16 years (Home) 6 months (Home)20 years (Clinic) 12 months (Home)

Data Collection: Types of Data Environmental air, water, soil, dust, noise levels samples from child’s environment (home, day care) Demographic Psychosocial Neurodevelopmental Biological samples from mother, father, child hair, saliva, urine, blood, breast milk, vaginal swabs Prenatal maternal diaries (e.g., nutrition, medications) ultrasounds Birth clinical exam data anthropometrics, blood pressure, dysmorphology, neurologic, dermatologic

Adjunct Studies Involve a portion of the NCS cohort, utilizing new or existing Study data and Study participants and/or their bio-specimens and/or environmental samples. Adjunct studies can take place at one or more Study Centers, on all or a portion of their Center participants. Evaluation criteria: Scientific merit and significance Design and methods Fit, value, and impact on NCS – Benefit to incorporating adjunct studies - Deepen or expand a NCS priority area - Relevance to NCS hypotheses - Proposed study benefits from incorporation into large longitudinal cohort study NCS investigator must be Co-Investigator More info: