Title of the journal club (Paper & authors; presenters) 1

Background What is the background evidence after your literature search? 2

The Clinical Question Participants Intervention Comparison Outcomes Design 3

Literature search Provide a simple flow chart of your literature. State why you have picked the current study for your presentation.

Aims & Objectives This is for the aims and objectives of your journal club. 5

Flow chart of the study Provide a simple flow chart of the study. Describe the study to the audience to help get a feel of the content and understand the methods used. 6

Details of the study Copy and paste useful charts or tables from the study paper, and explain their significance to the audience. This might need 2 or 3 slides. 7

GATE frame (a critical appraisal tool – use if appropriate) This is an instruction slide Apply the study to the GATE Frame and explain the steps to the audience. The next slide is the GATE Frame template. Reference: Jackson R, Ameratunga S, Broad J, Connor J, Lethaby A, Robb G, Wells S, Glasziou P, Heneghan C. The GATE frame: critical appraisal with pictures. Evid Based Med. 2006 Apr;11(2):35-8. PubMed PMID: 17213070. 8

GATE Frame (a critical appraisal tool – use if appropriate) Outcome Intervention Comparison Participants Intervention control Participants The outcome box shows that in the progesterone group there were 10 preterm births and in the placebo there were 20. Eligible population Source population 9

RAMMbo (a critical appraisal tool – use if appropriate) List the RAMMbo acronym stating if the study adhered to each part: Representative Allocation Maintenance Measurements blinded objective 10

Processing the evidence (a critical appraisal tool – use if appropriate) Please provide appropriate clinical measures (e.g. RRR, ARR and NNT) to help your audience interpret the results CATmaker (http://www.cebm.net/index.aspx?o=1216) from CEBM at Oxford could help you with this Example formula: Relative risk reduction (RRR): (CER - EER)/CER Absolute risk reduction (ARR): (CER - EER) Number needed to treat (NNT): 1/ARR or 1/(CER - EER) CER= control group event rate EER= experimental group event rate 11

Other discussion points Are there any other methodological issues to consider? Any questions with regards to results of this paper? 12

Authors’ conclusion What did the authors say in their conclusion? Was is appropriate and justified? 13

Applicability of the findings Do these results add to the existing evidence and guidelines? Would you change your practice?

Suggested reading

Acknowledgement Team members, etc.