Bringing Optogenetics to the Synapse

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Bringing Optogenetics to the Synapse Andreas Reiner, Joshua Levitz, Ehud Isacoff Neuron Volume 79, Issue 2, Pages 209-210 (July 2013) DOI: 10.1016/j.neuron.2013.07.009 Copyright © 2013 Elsevier Inc. Terms and Conditions

Figure 1 Optical Ablation of Neurotransmitter Release with InSynC (A) Targeting of miniSOG to a subset of presynaptic inputs (green fibers). (B) Light-induced singlet oxygen formation inhibits neurotransmitter release at terminals expressing miniSOG at vesicles. (C) Long-lasting, but reversible, inhibition of neurotransmission at a subset of presynaptic terminals in response to illumination with 480 nm light. Neuron 2013 79, 209-210DOI: (10.1016/j.neuron.2013.07.009) Copyright © 2013 Elsevier Inc. Terms and Conditions