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Conventional Synapses for Unconventional Cells

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1 Conventional Synapses for Unconventional Cells
Michael Beierlein, Wade G. Regehr  Neuron  Volume 46, Issue 5, Pages (June 2005) DOI: /j.neuron Copyright © 2005 Elsevier Inc. Terms and Conditions

2 Figure 1 Three Postsynaptic Targets of Climbing Fibers
(A) CFs (dark blue) form synapses with Purkinje cells (red), Bergmann glia (light blue), and NG2+ cells (light green). (B) (Left) CFs release glutamate onto Purkinje cell dendrites via conventional synapses and onto Bergmann glia via ectopic release. The conventional synapse consists of an active zone with a cluster of docked and reserve vesicles (white circles) opposed by a postsynaptic density and a cluster AMPA receptors (dark red), whereas ectopic release occurs at sites distant from active zones. (Right) CFs form conventional synapses with NG2+ cells. Neuron  , DOI: ( /j.neuron ) Copyright © 2005 Elsevier Inc. Terms and Conditions

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