A simple model describing the shape of the HIV epidemic with fits to sentinel HIV surveillance data. A simple model describing the shape of the HIV epidemic.

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A simple model describing the shape of the HIV epidemic with fits to sentinel HIV surveillance data. A simple model describing the shape of the HIV epidemic with fits to sentinel HIV surveillance data. (Left) Flow diagram illustrating the modelled population divided into three categories: not at risk; susceptible; and HIV infected. Initially a fraction f0 is at risk, but the fraction recruited into the “at risk” class is a function of the proportion of the existing population at risk. This allows the prevalence to stay high or fall precipitously in response to HIV associated mortality. The progress from HIV infection to death is assumed to be Weibull distributed. (Top right) Antenatal clinic (ANC) HIV prevalence data from Uganda with the best fit of the model (solid line) to the observed data. (Bottom right) ANC data from Benin with best fit of model to data.28 G P Garnett Sex Transm Infect 2002;78:7-12 ©2002 by BMJ Publishing Group Ltd