Study overview. Study overview. A, Schematic illustrating clinical trial design and the nature and number of tissue specimens available for downstream.

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Study overview. Study overview. A, Schematic illustrating clinical trial design and the nature and number of tissue specimens available for downstream analysis. B, Example photomicrographs of H&E-stained RP specimens from the treatment arm demonstrating differing degrees of treatment score. See also Supplementary Fig. S1. C, Schematic showing the breakdown of genomic and transcriptomic profiling techniques applied to each patient in the cohort. The effect of treatment on serum prostate-specific antigen (PSA) levels is also provided. Himisha Beltran et al. Clin Cancer Res 2017;23:6802-6811 ©2017 by American Association for Cancer Research