Risk factors for severe postoperative nausea and vomiting in a randomized trial of nitrous oxide-based vs nitrous oxide-free anaesthesia K. Leslie, P.S.

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Presentation transcript:

Risk factors for severe postoperative nausea and vomiting in a randomized trial of nitrous oxide-based vs nitrous oxide-free anaesthesia K. Leslie, P.S. Myles, M.T.V. Chan, M.J. Paech, P. Peyton, A. Forbes, D. McKenzie British Journal of Anaesthesia Volume 101, Issue 4, Pages 498-505 (October 2008) DOI: 10.1093/bja/aen230 Copyright © 2008 British Journal of Anaesthesia Terms and Conditions

Fig 1 Multivariate odds ratios (95% CIs) for PONV for preoperative and intraoperative predictors. British Journal of Anaesthesia 2008 101, 498-505DOI: (10.1093/bja/aen230) Copyright © 2008 British Journal of Anaesthesia Terms and Conditions

Fig 2 Recursive partitioning/CART analysis of factors predicting severe PONV. BIS monitoring and N2O were entered into CART first, because a significant interaction between them was identified. CART splits the variable ‘duration of anaesthesia’ at 3.32 h. Odds ratios (OR) (95% CIs and P-values) are reported from analysis that were adjusted for age <55 yr and abdominal surgery (factors that CART did not include in the model). The subgroup of patients with the lowest risk of PONV (BIS-monitored and N2O-free) served as the reference group. British Journal of Anaesthesia 2008 101, 498-505DOI: (10.1093/bja/aen230) Copyright © 2008 British Journal of Anaesthesia Terms and Conditions