Presentation is loading. Please wait.

Presentation is loading. Please wait.

Effect of prophylactic 5-HT3 receptor antagonists on pruritus induced by neuraxial opioids: a quantitative systematic review†  M.-P. Bonnet, E. Marret,

Similar presentations


Presentation on theme: "Effect of prophylactic 5-HT3 receptor antagonists on pruritus induced by neuraxial opioids: a quantitative systematic review†  M.-P. Bonnet, E. Marret,"— Presentation transcript:

1 Effect of prophylactic 5-HT3 receptor antagonists on pruritus induced by neuraxial opioids: a quantitative systematic review†  M.-P. Bonnet, E. Marret, J. Josserand, F.J. Mercier  British Journal of Anaesthesia  Volume 101, Issue 3, Pages (September 2008) DOI: /bja/aen202 Copyright © 2008 British Journal of Anaesthesia Terms and Conditions

2 Fig 1 Flow chart of systematic research.
British Journal of Anaesthesia  , DOI: ( /bja/aen202) Copyright © 2008 British Journal of Anaesthesia Terms and Conditions

3 Fig 2 Effect of 5-HT3 antagonists on the risk of pruritus after administration of spinal or epidural opioids (OR, odds ratio). British Journal of Anaesthesia  , DOI: ( /bja/aen202) Copyright © 2008 British Journal of Anaesthesia Terms and Conditions

4 Fig 3 L'Abbé plot of the risk of pruritus for 5-HT3 antagonists vs placebo. Closed circles, incidence of pruritus was significantly (P<0.05) lower in the 5-HT3 antagonist group; open circles, no significant difference in the 5-HT3 antagonist group compared with the placebo group. British Journal of Anaesthesia  , DOI: ( /bja/aen202) Copyright © 2008 British Journal of Anaesthesia Terms and Conditions

5 Fig 4 Effect of 5-HT3 antagonists on the risk of pruritus after administration of spinal or epidural opioids in patients undergoing Caesarean section (OR, odds ratio). British Journal of Anaesthesia  , DOI: ( /bja/aen202) Copyright © 2008 British Journal of Anaesthesia Terms and Conditions

6 Fig 5 Funnel plot with 95% CI for all trials investigating the incidence of pruritus in patients receiving neuraxial opioids and undergoing all surgical procedures and labour (OR, odds ratio). British Journal of Anaesthesia  , DOI: ( /bja/aen202) Copyright © 2008 British Journal of Anaesthesia Terms and Conditions

7 Fig 6 Effect of 5-HT3 antagonists on the pruritus intensity score after administration of neuraxial opioids (WMD, weighted mean difference). British Journal of Anaesthesia  , DOI: ( /bja/aen202) Copyright © 2008 British Journal of Anaesthesia Terms and Conditions

8 Fig 7 Effect of 5-HT3 antagonists on the treatment request for pruritus after administration of neuraxial opioids (OR, odds ratio). British Journal of Anaesthesia  , DOI: ( /bja/aen202) Copyright © 2008 British Journal of Anaesthesia Terms and Conditions


Download ppt "Effect of prophylactic 5-HT3 receptor antagonists on pruritus induced by neuraxial opioids: a quantitative systematic review†  M.-P. Bonnet, E. Marret,"

Similar presentations


Ads by Google