RAD51 interacts with SUMO-1 through its SIM

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RAD51 interacts with SUMO-1 through its SIM RAD51 interacts with SUMO-1 through its SIM. (A) The SUMO-interacting motif (SIM) is evolutionally conserved in eukaryotic RAD51 homologues. RAD51 interacts with SUMO-1 through its SIM. (A) The SUMO-interacting motif (SIM) is evolutionally conserved in eukaryotic RAD51 homologues. Amino acid residues matching the consensus sequences of SIM (V/I-A-V/I-V/I) are shown in red. (B) Two-hybrid analysis of RAD51 and SUMO-1. The growth of two independent transformants on SD +His (left) and SD –His (middle) plates was examined for each combination of vectors indicated (right). Hiroki Shima et al. J Cell Sci 2013;126:5284-5292 © 2013. Published by The Company of Biologists Ltd