Removing Barriers in the HCV Cascade of Care
Program Overview
HCV Burden of Disease
Worldwide HCV Prevalence (2015)
Global Annual Mortality
Disability From Liver Disease Has Increased (2006-2016)
Outline of HCV Long-Term Complications Natural History of Hepatitis C
Progression to Cirrhosis
Progression to Cirrhosis (cont)
Extrahepatic Manifestations of HCV Infection
Improving the HCV Cascade of Care
WHO Vision
HCV Cascade of Care (British Columbia, Canada)
HCV Cascade of Care (British Columbia, Canada) (cont)
HCV Cascade of Care (British Columbia, Canada) (cont)
Screening Strategies
ELISA Assays
NAT Testing (rtPCR or TMA)
Point-of-Care Tests
Rapid Diagnostic Tests (RDT)
Dried Blood Spots (DBS)
Confirmation of Replication
Screening Linkage to Care
Decentralized Screening and Care
Simplified Pretherapeutic Assessment
EASL Recommendations on the Treatment of Hepatitis C 2018
Treatment Monitoring
Simplified Treatment Monitoring
HCV Elimination Strategies
HCV Elimination Strategies
HCV Elimination Strategies
Micro-Elimination Target Groups
US Veterans
Concluding Remarks
Abbreviations
Abbreviations (cont)