Removing Barriers in the HCV Cascade of Care

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Presentation transcript:

Removing Barriers in the HCV Cascade of Care

Program Overview

HCV Burden of Disease

Worldwide HCV Prevalence (2015)

Global Annual Mortality

Disability From Liver Disease Has Increased (2006-2016)

Outline of HCV Long-Term Complications Natural History of Hepatitis C

Progression to Cirrhosis

Progression to Cirrhosis (cont)

Extrahepatic Manifestations of HCV Infection

Improving the HCV Cascade of Care

WHO Vision

HCV Cascade of Care (British Columbia, Canada)

HCV Cascade of Care (British Columbia, Canada) (cont)

HCV Cascade of Care (British Columbia, Canada) (cont)

Screening Strategies

ELISA Assays

NAT Testing (rtPCR or TMA)

Point-of-Care Tests

Rapid Diagnostic Tests (RDT)

Dried Blood Spots (DBS)

Confirmation of Replication

Screening Linkage to Care

Decentralized Screening and Care

Simplified Pretherapeutic Assessment

EASL Recommendations on the Treatment of Hepatitis C 2018

Treatment Monitoring

Simplified Treatment Monitoring

HCV Elimination Strategies

HCV Elimination Strategies

HCV Elimination Strategies

Micro-Elimination Target Groups

US Veterans

Concluding Remarks

Abbreviations

Abbreviations (cont)