Conveying Information Department of Biology, WCU
Receptors Classification 1. Type of stimuli Mechanical (touch, BP) Thermal (internal & external) Photo (light detection) Chemical (blood pH)
Receptors 2. Body region Exteroceptors (touch, temp) Interoceptors (blood pH, BP, temp)
Receptors 3. Structural complexity Simple: monitor sensory information A. free dendritic endings (skin, mucosal membrane) B. encapsulated endings (mechanoreceptors)
Receptors Complex : sense organs
Graded Potentials Receptor potentials
Graded Potentials Generator potential
Graded potentials Characteristics greater stimulus = greater response maintained provided stimulus maintained Adaptation over time Receptor types A. phasic (touch) B. tonic (pain)
Graded potentials Phasic: adapt quickly Tonic: adapt slowly
Graded Potentials Every potential other than an AP EPSP/IPSP’s GP’s AP’s AP’s
Transmission inhibition Diseases, toxins, drugs 1. Myasthenia gravis shortage of Ach receptors swallowing, talking, muscle weakness 2. Paralysis binding to Ach receptors (curare) 3. Tetradotoxin decreases Na+ conduction