Annual Burden and Costs of Hospitalization for High-Need, High-Cost Patients With Chronic Gastrointestinal and Liver Diseases  Nghia H. Nguyen, Rohan Khera, Lucila Ohno-Machado, William J. Sandborn, Siddharth Singh  Clinical Gastroenterology and Hepatology  Volume 16, Issue 8, Pages 1284-1292.e30 (August 2018) DOI: 10.1016/j.cgh.2018.02.015 Copyright © 2018 AGA Institute Terms and Conditions

Figure 1 Burden of inflammatory bowel diseases. (A) Total days spent in the hospital per month, and (B) total costs of hospitalization per month, by deciles. High-need, high-cost patients were defined as patients in the highest decile by the total days spent in the hospital per month. The white dot represents the median, the box plots represent the interquartile range, and whiskers represent 5th and 95th percentiles within that decile. Clinical Gastroenterology and Hepatology 2018 16, 1284-1292.e30DOI: (10.1016/j.cgh.2018.02.015) Copyright © 2018 AGA Institute Terms and Conditions

Figure 2 Burden of chronic liver diseases. (A) Total days spent in the hospital per month, and (B) total costs of hospitalization per month, by deciles. Clinical Gastroenterology and Hepatology 2018 16, 1284-1292.e30DOI: (10.1016/j.cgh.2018.02.015) Copyright © 2018 AGA Institute Terms and Conditions

Figure 3 Burden of functional gastrointestinal diseases. (A) Total days spent in the hospital per month, and (B) total costs of hospitalization per month, by deciles. Clinical Gastroenterology and Hepatology 2018 16, 1284-1292.e30DOI: (10.1016/j.cgh.2018.02.015) Copyright © 2018 AGA Institute Terms and Conditions

Figure 4 Burden of gastrointestinal hemorrhage. (A) Total days spent in the hospital per month, and (B) total costs of hospitalization per month, by deciles. Clinical Gastroenterology and Hepatology 2018 16, 1284-1292.e30DOI: (10.1016/j.cgh.2018.02.015) Copyright © 2018 AGA Institute Terms and Conditions

Supplementary Figure 1 Selection of patients for constructing the study cohort from hospital records in the Nationwide Readmissions Database 2013. Clinical Gastroenterology and Hepatology 2018 16, 1284-1292.e30DOI: (10.1016/j.cgh.2018.02.015) Copyright © 2018 AGA Institute Terms and Conditions

Supplementary Figure 2 Total number of hospitalizations per month, by deciles in patients with (A) inflammatory bowel diseases, (B) chronic liver diseases, (C) functional gastrointestinal diseases, (D) gastrointestinal bleeding, and (E) pancreatic diseases. The red dot represents the median, the box plots represent the interquartile range, and whiskers represent the 5th and 95th percentiles within that decile. Clinical Gastroenterology and Hepatology 2018 16, 1284-1292.e30DOI: (10.1016/j.cgh.2018.02.015) Copyright © 2018 AGA Institute Terms and Conditions

Supplementary Figure 3 Variability in the total days spent in the hospital per month by HNHC patients with (A) inflammatory bowel diseases, (B) chronic liver diseases, (C) functional gastrointestinal diseases, (D) gastrointestinal bleeding, and (E) pancreatic diseases. The red dot represents the median, the box plots represent the interquartile range, and whiskers represent the 5th and 95th percentiles within that centile. Overall, the X-axis represents patients at the 90th, 91st, 92nd … 99th centile, by length of stay. Clinical Gastroenterology and Hepatology 2018 16, 1284-1292.e30DOI: (10.1016/j.cgh.2018.02.015) Copyright © 2018 AGA Institute Terms and Conditions

Supplementary Figure 4 Variability in total hospitalization costs per month by HNHC patients with (A) inflammatory bowel diseases, (B) chronic liver diseases, (C) functional gastrointestinal diseases, (D) gastrointestinal bleeding, and (E) pancreatic diseases. The red dot represents the median, the box plots represent the interquartile range, and whiskers represent the 5th and 95th percentiles within that centile. Overall, the X-axis represents patients at the 90th, 91st, 92nd … 99th centile, by length of stay. Clinical Gastroenterology and Hepatology 2018 16, 1284-1292.e30DOI: (10.1016/j.cgh.2018.02.015) Copyright © 2018 AGA Institute Terms and Conditions

Supplementary Figure 5 Causes of hospitalizations based on primary discharge diagnoses grouped by CCS codes and organ systems, in patients in the 1st, 5th, and 10th deciles, with (A) inflammatory bowel diseases, (B) chronic liver diseases, (C) functional gastrointestinal diseases, (D) gastrointestinal bleeding, and (E) pancreatic diseases. Clinical Gastroenterology and Hepatology 2018 16, 1284-1292.e30DOI: (10.1016/j.cgh.2018.02.015) Copyright © 2018 AGA Institute Terms and Conditions

Supplementary Figure 5 Causes of hospitalizations based on primary discharge diagnoses grouped by CCS codes and organ systems, in patients in the 1st, 5th, and 10th deciles, with (A) inflammatory bowel diseases, (B) chronic liver diseases, (C) functional gastrointestinal diseases, (D) gastrointestinal bleeding, and (E) pancreatic diseases. Clinical Gastroenterology and Hepatology 2018 16, 1284-1292.e30DOI: (10.1016/j.cgh.2018.02.015) Copyright © 2018 AGA Institute Terms and Conditions

Supplementary Figure 6 Burden of pancreatic diseases. (A) Total days spent in the hospital per month, and (B) total costs of hospitalization per month, by deciles in patients with pancreatic diseases. The red dot represents the median, the box plots represent the interquartile range, and whiskers represent the 5th and 95th percentiles within that decile. Clinical Gastroenterology and Hepatology 2018 16, 1284-1292.e30DOI: (10.1016/j.cgh.2018.02.015) Copyright © 2018 AGA Institute Terms and Conditions