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Histologic Changes in Liver Tissue From Patients With Chronic Hepatitis B and Minimal Increases in Levels of Alanine Aminotransferase: A Meta-analysis.

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Presentation on theme: "Histologic Changes in Liver Tissue From Patients With Chronic Hepatitis B and Minimal Increases in Levels of Alanine Aminotransferase: A Meta-analysis."— Presentation transcript:

1 Histologic Changes in Liver Tissue From Patients With Chronic Hepatitis B and Minimal Increases in Levels of Alanine Aminotransferase: A Meta-analysis and Systematic Review  Long H. Nguyen, David Chao, Joseph K. Lim, Walid Ayoub, Mindie H. Nguyen  Clinical Gastroenterology and Hepatology  Volume 12, Issue 8, Pages (August 2014) DOI: /j.cgh Copyright © 2014 AGA Institute Terms and Conditions

2 Figure 1 Flow diagram of studies identified and selected for inclusion into the meta-analysis. DDW, Digestive Disease Week®. Clinical Gastroenterology and Hepatology  , DOI: ( /j.cgh ) Copyright © 2014 AGA Institute Terms and Conditions

3 Figure 2 Proportion of patients with ALT 1-2 × ULN and significant histological changes. Clinical Gastroenterology and Hepatology  , DOI: ( /j.cgh ) Copyright © 2014 AGA Institute Terms and Conditions

4 Figure 3 Funnel plot for studies included in the primary analysis.
Clinical Gastroenterology and Hepatology  , DOI: ( /j.cgh ) Copyright © 2014 AGA Institute Terms and Conditions

5 Figure 4 Proportion of HBeAg+ patients with ALT 1-2 × ULN and significant histological changes. Clinical Gastroenterology and Hepatology  , DOI: ( /j.cgh ) Copyright © 2014 AGA Institute Terms and Conditions

6 Figure 5 Proportion of HBeAg- patients with ALT 1-2 × ULN and significant histological changes. Clinical Gastroenterology and Hepatology  , DOI: ( /j.cgh ) Copyright © 2014 AGA Institute Terms and Conditions


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