Factors Associated with Peripheral Blood Stem Cell Yield in Volunteer Donors Mobilized with Granulocyte Colony-Stimulating Factors: The Impact of Donor.

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Presentation transcript:

Factors Associated with Peripheral Blood Stem Cell Yield in Volunteer Donors Mobilized with Granulocyte Colony-Stimulating Factors: The Impact of Donor Characteristics and Procedural Settings Tso-Fu Wang, Shu-Hui Wen, Rong-Long Chen, Chi-Jui Lu, Ya-Jun Zheng, Shang-Hsien Yang, Sung-Chao Chu, Ruey-Ho Kao, Shu- Huey Chen Biology of Blood and Marrow Transplantation Volume 14, Issue 11, Pages 1305-1311 (November 2008) DOI: 10.1016/j.bbmt.2008.09.002 Copyright © 2008 American Society for Blood and Marrow Transplantation Terms and Conditions

Figure 1 Receiver operating characteristic (ROC) curve for day 1 CD34+ cell yields from healthy donors. The ROC curve for day 1 CD34+ cell yields with poor mobilization as measure by traditional criteria (< 2 × 106 CD34+ cells/kg of recipient BW) is shown. In predicting day 1 poor mobilization, a cutoff value of < 10 × 106 for day 1 CD34+ cell yield gives a sensitivity of 94.6% and a specificity of 91.7%. Biology of Blood and Marrow Transplantation 2008 14, 1305-1311DOI: (10.1016/j.bbmt.2008.09.002) Copyright © 2008 American Society for Blood and Marrow Transplantation Terms and Conditions