A. K. Staehr-Rye, C. S. Meyhoff, F. T. Scheffenbichler, M. F

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Presentation transcript:

High intraoperative inspiratory oxygen fraction and risk of major respiratory complications A.K. Staehr-Rye, C.S. Meyhoff, F.T. Scheffenbichler, M.F. Vidal Melo, M.R. Gätke, J.L. Walsh, K.S. Ladha, S.D. Grabitz, M.I. Nikolov, T. Kurth, L.S. Rasmussen, M. Eikermann British Journal of Anaesthesia Volume 119, Issue 1, Pages 140-149 (July 2017) DOI: 10.1093/bja/aex128 Copyright © 2017 The Author(s) Terms and Conditions

Fig 1 Flow of patients through study. British Journal of Anaesthesia 2017 119, 140-149DOI: (10.1093/bja/aex128) Copyright © 2017 The Author(s) Terms and Conditions

Fig 2 Multivariable logistic regression analysis examining the association between median intraoperative inspiratory oxygen fraction F I O 2 and risk of major postoperative respiratory complications in each subgroup of patients based on their estimated propensity score for receiving high F I O 2 . Patients are divided into five groups based on their propensity score for being in the quintile with the highest median F I O 2 values ( F I O 2 >0.63). In each subgroup, the odds of developing a respiratory complication in the highest quintile of F I O 2 is compared with the odds in the lowest quintile of F I O 2 presented as odds ratio [95% confidence interval]. The logistic regression analysis is adjusted for sex, age, BMI, ASA classification, score for prediction of respiratory complications, Charlson comorbidity index, pre-existing chronic obstructive pulmonary disease, duration of anaesthesia, opioids, volatile anaesthetics, fluid administration, units of packed red blood cells, PEEP, tidal volume per predicted body weight, non-depolarizing neuromuscular blocking agents, emergency surgery, ambulatory surgery, Procedure Severity Score for morbidity, and surgical type. British Journal of Anaesthesia 2017 119, 140-149DOI: (10.1093/bja/aex128) Copyright © 2017 The Author(s) Terms and Conditions