Fig. 8 SOD2 overexpression in normal tissues does not compromise the cytotoxic efficacy of RT. SOD2 overexpression in normal tissues does not compromise.

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Conserved Shifts in the Gut Microbiota Due to Gastric Bypass Reduce Host Weight and Adiposity by Alice P. Liou, Melissa Paziuk, Jesus-Mario Luevano, Sriram.

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Fig. 1. TP is highly expressed in myeloma.

Fig. 6. AZD6738 induces DNA damage and apoptosis and exhibits antitumor efficacy in xenograft models of high-risk medulloblastoma and neuroblastoma. AZD6738.

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Fig. 2 miRNA181a targets NFAT5 in human CD4+ T cells.

In vivo prophylactic and therapeutic efficacy of C12G6 in mice

Fig. 6. Combinatorial VCPI and OV M1 treatment is efficacious in vivo and ex vivo. Combinatorial VCPI and OV M1 treatment is efficacious in vivo and ex.

Fig. 8. In vivo suppression of MM by CMLD

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MRSA virulence proteins cause LMC death and diminished CLV function

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Fig. 1. Identification of SE-associated lncRNAs.

Maraba treatment sensitizes 4T1 tumors to immune checkpoint blockade

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Fig. 5. Vascularization of human liver seed grafts.

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Dot plots of trisomic versus fetal fractions for cohorts 1 and 2

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Fig. 5 Local gel scaffold for T cell memory response.

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Fig. 6 Photoreceptor cell survival in the RCS rat retina after transplantation with hESC-RPE cell sheets. Photoreceptor cell survival in the RCS rat retina.

Fig. 5 ALRN-6924 shows robust antileukemic activity in primary AML cells and in vivo. ALRN-6924 shows robust antileukemic activity in primary AML cells.

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Fig. 1 Irradiation with 50 Gy/3 fractions generates LAE characterized by SOD2 depletion and CTGF overexpression. Irradiation with 50 Gy/3 fractions generates.

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Fig. 6. Combinatorial VCPI and OV M1 treatment is efficacious in vivo and ex vivo. Combinatorial VCPI and OV M1 treatment is efficacious in vivo and ex.

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Fig. 1. Schematic description of whole-exome or targeted next-generation sequencing analyses. Schematic description of whole-exome or targeted next-generation.

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Fig. 8 SOD2 overexpression in normal tissues does not compromise the cytotoxic efficacy of RT. SOD2 overexpression in normal tissues does not compromise the cytotoxic efficacy of RT. (A) Conditioned medium experiment to assess transmissibility of SOD2 overexpression after exposure of target cells (HeLa) to supernatant (HeLa-SOD2 supernatant) taken from producer cells (HeLa_SOD2) (blot representative of n = 3 biological repeats). (B) Schematic of the in vivo tumor recurrence model showing tumor (red arrow) growing in an SIEA flap (paddle outline dashed white). Animals with tumors greater than 2 cm in diameter were deemed to have exceeded the experimental severity limit and euthanized. (C) Tumor volume growth (mean ± SEM) for Mat B III tumors after RT in flaps infected with LVSOD2, LVeGP, or sham (PBS) (n = 5 animals per group). (D) Individual growth curves for tumors growing in sham (PBS)–infected and unirradiated, sham (PBS)–infected and irradiated (20 Gy/5 fractions), LVSOD-infected and irradiated (20 Gy/5 fractions), or LVeGFP-infected and irradiated (20 Gy/5 fractions) flaps (n = 5 animals per group). (E) Kaplan-Meier plot of survival to severity limit (2- cm tumor diameter) for animals with Mat B III tumors grown in sham (PBS)–, LVSOD2-, or LVeGFP-infected flaps. Median survival is shown at the bottom right. n/a, not applicable. Aadil A. Khan et al., Sci Transl Med 2018;10:eaar2041 Published by AAAS