One of the great exchange systems in the body Gas exchange One of the great exchange systems in the body © 2016 Paul Billiet ODWS
Breathing ≠ Respiration Ventilation is the pumping of air into and out of the alveoli of the lungs Gas exchange is the exchange of CO2 and O2 between the air in the alveoli and the blood in the capillaries Cell respiration is the process that consumes the O2 and produces the CO2. It takes place in all the cells. © 2016 Paul Billiet ODWS
The exchange surface 70m2 of air meets 60m2 of blood www.european-lung-foundation.org/uploads/Docu... © 2016 Paul Billiet ODWS
Capillaries Capillary network of a rat lung © 2016 Paul Billiet ODWS www.southalabama.edu/.../clip_image002_0010.jpg © 2016 Paul Billiet ODWS
Alveoli (300 million) © 2016 Paul Billiet ODWS www.european-lung-foundation.org/uploads/Docu... © 2016 Paul Billiet ODWS
Alveolar wall Type 1 & type 2 pneumocytes © 2016 Paul Billiet ODWS www.european-lung-foundation.org/uploads/Docu... Type 1 & type 2 pneumocytes © 2016 Paul Billiet ODWS
Adaptations Large surface area 70m2 Thin barrier to diffusion 0.4µm (type 1 pneumocytes) Constant renewal of air and blood, maintains concentration gradient Surfactant stops sides sticking (type 2 pneumocytes). warriors.warren.k12.il.us/dburke/alveoli2.jpg © 2016 Paul Billiet ODWS
The ventilation system Intercostal muscles Trachea Bronchus Bronchioles Diaphragm Heart Lung Ribs Larynx Cartilage rings © 2016 Paul Billiet ODWS
Ventilation © 2016 Paul Billiet ODWS http://www.merck.com/mmhe/sec04/ch038/ch038e.html © 2016 Paul Billiet ODWS
Ventilation - Inhaling The diaphragm muscles contract and the diaphragm is pulled down The external intercostals contract and the ribs rise The lungs expand with the thorax and the lung volume increases The pressure in the thorax falls, air is drawn into the lungs. © 2016 Paul Billiet ODWS
Ventilation - Exhaling The diaphragm muscle relax and the elastic lung tissue retracts The external intercostals relax and the ribs fall The lung volume diminishes and air leaves the lungs Air may be forced out by the internal intercostals and abdominal muscles contracting to pull the ribs down. © 2016 Paul Billiet ODWS