Figure 4 The heterotrimeric G-protein Gz is involved in the inhibitory effects of PGE1 on endocytosis. The heterotrimeric G-protein Gz is involved in the.

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Figure 4 The heterotrimeric G-protein Gz is involved in the inhibitory effects of PGE1 on endocytosis. The heterotrimeric G-protein Gz is involved in the inhibitory effects of PGE1 on endocytosis. (A) PGE1-induced inhibition of endocytosis was studied in the presence of the Gz blocking peptide (Gz/blocking) or a scrambled peptide (Gz/scrambled) as a control. A second control was endocytosis in the presence of the Gz scrambled peptide. (B) Summary of the endocytotic actions studied in the test and control conditions, as labeled, in the early (left panel) and late (right panel) phases. The early and late phases of endocytosis are indicated as white and gray, respectively. Data were analyzed from 17 to 23 cells for each experimental condition. Protocols were analogous to those used in the experiments of Fig. 2. *P<0.05, **P<0.01, #NS. Ying Zhao et al. J Endocrinol 2016;229:287-294 © 2016 Society for Endocrinology