Osteoarthritis and Cartilage

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Changes in micro-architecture of subchondral bone in knee osteoarthritis Sam de Groen Supervisors: Prof Karen J Reynolds, Dr Egon Perilli Associates: Bryant.

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Osteoarthritis and Cartilage Linking proximal tibia bone microarchitecture to in vivo dynamic knee joint loads in end- stage knee osteoarthritis B.C. Roberts, D. Thewlis, L.B. Solomon, G. Mercer, K.J. Reynolds, E. Perilli Osteoarthritis and Cartilage Volume 24, (April 2016) DOI: 10.1016/j.joca.2016.01.201 Copyright © 2016 Terms and Conditions

Figure 1. (a) 3D micro-CT image of a right tibial plateau Figure 1. (a) 3D micro-CT image of a right tibial plateau. (b) Micro-CT cross-section image of subchondral bone, showing the positions (in red colour) of the four volumes of interest for analysis, in antero-medial (AM), antero-lateral (AL), postero-medial (PM), postero-lateral (PL) location. Osteoarthritis and Cartilage 2016 24, DOI: (10.1016/j.joca.2016.01.201) Copyright © 2016 Terms and Conditions

Figure 2. (a) average BV/TV in the four proximal tibia ROIs (. p<0 Figure 2. (a) average BV/TV in the four proximal tibia ROIs (*p<0.05, **p<0.01); (b) Scatter plot with best fit line for 'BV/TV vs. peak ERM'. Osteoarthritis and Cartilage 2016 24, DOI: (10.1016/j.joca.2016.01.201) Copyright © 2016 Terms and Conditions