Wang-Zwische Double-Lumen Cannula Leads to Total Cavopulmonary Support in a Failing Fontan Sheep Model Dongfang Wang, MD, PhD, Mark Plunkett, MD, James.

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Wang-Zwische Double-Lumen Cannula Leads to Total Cavopulmonary Support in a Failing Fontan Sheep Model Dongfang Wang, MD, PhD, Mark Plunkett, MD, James Lynch, MD, Xiaoqin Zhou, MD, Cherry Ballard-Croft, PhD, Joseph B. Zwischenberger, MD The Annals of Thoracic Surgery Volume 91, Issue 6, Pages 1956-1960 (June 2011) DOI: 10.1016/j.athoracsur.2011.02.031 Copyright © 2011 The Society of Thoracic Surgeons Terms and Conditions

Fig 1 (A) The cavopulmonary assist device consists of a Wang-Zwiche double-lumen catheter (DLC; AvalonElite, Avalon Laboratories LLC, Rancho Dominguez, CA) and a CentriMag Pump (Levitronix Waltham, MA). The DLC removes venous blood from superior vena cava (SVC)/inferior vena cava (IVC) and delivers it to the right pulmonary artery (RPA). (B) In the sheep model of failing Fontan circulation, the extracardiac conduit diverts total venous blood from SVC/IVC to RPA. (LA = left atrium; LPA = left pulmonary artery; LV = left ventricle; RA = right atrium; RV = right ventricle.) The Annals of Thoracic Surgery 2011 91, 1956-1960DOI: (10.1016/j.athoracsur.2011.02.031) Copyright © 2011 The Society of Thoracic Surgeons Terms and Conditions

Fig 2 Hemodynamic stability of cavopulmonary support. (A) Normal baseline. (B) Failing Fontan circulation. The systolic arterial blood pressure and mean pulmonary artery pressure (mPAP) were reduced, and central venous pressure (CVP) was elevated after total cavopulmonary conversion. (C) The abnormal failing Fontan hemodynamic variables were completely corrected by cavopulmonary support. The Annals of Thoracic Surgery 2011 91, 1956-1960DOI: (10.1016/j.athoracsur.2011.02.031) Copyright © 2011 The Society of Thoracic Surgeons Terms and Conditions