Hypothalamus Visceral Afferent & Motor Paths Lab 13 Hypothalamus Visceral Afferent & Motor Paths

6 1 11 7 2 13 12 8 3 9 4 5 10 hypothalamic sulcus anterior commissure infundibulum thalamus 7 lamina terminalis 2 13 12 Sphenoidal sinus Hypophysis hypo- thalamus 8 3 optic chiasm mammillary bodies (gross) 9 infundibulum 4 general location, median eminence 5 tuber cinereum 10

1 2 3

What is the ~location of the: Anterior Hypothalamus Region? Middle Hypothalamus Region? Posterior Hypothalamus Region?

1 5 Basal Forebrain 6 2 3 4

1 (depression) Hypophysial Fossa 2 (bony opening) Optic Canal

1 (opening) 3 2 (nucleus) 4 (connection) 5 (nucleus) 6 (area) 7 Anterior Horn of Lateral Ventricle 3 2 (nucleus) Paraventricular Nuclei Fornix 4 (connection) Anterior Comissure 5 (nucleus) Supraoptic Nuclei 6 (area) Preoptic area of hypothalamus - GnRH 7 (nuclues) Suprachiasmatic Nuclei 10 Optic Tract 8 Infundibular Stalk 3rd Ventricle 9

What region of hypothalamus is shown here? Basal Forebrain 2 Uncus What region of hypothalamus is shown here? Anterior Hypothalamus

What hormone is produced here? Magnocellular secreting neurons – project to the spinal cord and posterior hypophysis (neurohypophysis) ADH Also made in magnocellular neurons and sent via axons to neurohypophysis 1 What hormone is produced here?

What region of hypothalamus is shown here? anterior horn, lateral ventricle 1 septum pellucidum 2 Interventricular foramen 3 genu, IC 4 III ventricle 5 VAP position of MFB 9 (fibers) 8 fornix amygdala 6 optic tract 7 What region of hypothalamus is shown here? Middle Hypothalamus

6 7 8 9 11 10 13 (nucleus) 14 12 1 (nucleus) 2 (nucleus) 5 4 3 Cingulate gyrus 6 1 (nucleus) 2 (nucleus) VPL + VPM (with taste area) Insular cortex 5 mammillo- thalamic tract fornix 4 fornix 7 3 mammillo- thalamic tract 8 anterior nucleus 9 mammillary nuclei 11 MFB 10 position of tuberomammilary nucleus (TMN) DLF location (medial) 13 (nucleus) 14 hippocampal formation 12

1 6 5 (region) (nucleus) 2 3 4 PAG PAG (with fibers of DLF + continuation of MFB) 1 gen. location of EW nuc. 6 (nucleus) PAG 5 (region) Edinger Westphal Nuc. 2 Edinger Westphal Nuc. 3 PAG (with fibers of DLF + continuation of MFB) 4

2 (fibers) 1 (nucleus) 3 (nucleus) 4 (fibers) Dorsal longitudinal Fasciculus (DLF) 2 (fibers) 1 (nucleus) Locus ceruleus parabrachial nucleus 3 (nucleus) Reticular formation with Ascending/descending fibers from MFB 4 (fibers)

2 3 (nucleus) 4 (fibers) 6 5 1 (nucleus) 7 (nucleus) 8 (nucleus) DLF 2 dorsal motor nucleus of vagus n. 3 (nucleus) reticular formation with descending hypothalamic fibers 4 (fibers) 6 VLM 5 VLM 1 (nucleus) Solitary nucleus And tract Solitary nucleus And tract 7 (nucleus) dorsal motor nucleus of vagus n. 8 (nucleus) VLM (ventrolateral medulla) – area w/ visceral motor centers like digestion & cardiovascular

Descending Hypothalamic System 1 Intermediolateral horn

1 Descending Hypothalamic System Sacral Parasympathetic Nuclei – in the intermediate zone

3 (nucleus) 1 (nerves) 7 (nuclei) 4 (fibers) 5 (nucleus) 6 (fibers) 2 Nerve roots IX & X dorsal motor nucleus of vagus n. 1 (nerves) 3 (nucleus) salivatory nuclei (of VII and IX). 7 (nuclei) Solitary tract 4 (fibers) Solitary nucleus 5 (nucleus) reticular formation with hypo- thalamic fibers 6 (fibers) 2 VLM

1 2

1 2 3

5 4 6 3 1 2 7 8 (fibers) anterior cingulate cortex amygdala uncus ventromedial prefrontal ctx 3 Orbito- frontal ctx. 1 olfactory tract 2 Orbito- frontal ctx. 7 olfactory tract 8 (fibers)