MCB Exam 3 Review Fall 2018

Cytoplasmic streaming Continuous motion of the cytoplasm typically occurring in large cells Multicellular organisms (animal, plant, single cell prokaryotes) tend to be limited in size (1-100um) likely reflecting a limit on effective diffusion Current hypothesis: Streaming is a form of compensation for larger cell sizes Molecular motors (myosin-actin) along the cytoskeleton  circulation of cytoplasmic fluid Enhances nutrient transport, facilitates metabolite interactions, moves organelles e.g. chloroplasts, etc

Cells of the Nervous System (Mercer) Know all the cell types presented in lecture – neurons, glia What are the different types of cells in each category? What roles do they play? Understand how signals are transferred across a neuronal synapse Chemical vs electrical Know what happens at the neuromuscular junction Understand the role of neurotransmitters Examples? What do they do? Excitatory vs inhibitory?

Plant Cell Biology (Dixit) What makes plant cells different from animal cells? Cell division Membrane transporters Organelles Cytoskeleton Osmotic regulation/maintenance of cell volume Modes of intracellular transport

ECM and Cell-Matrix Interactions (Miner) ECM – key proteins, function Basement membrane – key proteins, function Role of integrins - How are they activated? What do they bind? Why do we need them? Collagen vs elastin synthesis – what happens if something goes wrong? Know the diseases discussed in these lectures Collagen/elastin = extremely important and ubiquitous structural proteins

Prions (True)

Good luck!