Fig. 1. Working principle of the plasmon sensor chip (NPS) for tEVs.

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Presentation transcript:

Fig. 1. Working principle of the plasmon sensor chip (NPS) for tEVs. Working principle of the plasmon sensor chip (NPS) for tEVs. (A) EV binding to the nanopore surface via monoclonal antibody (mAb) immobilized on the gold surface causes a spectral shift of light transmitted through the nanopores. (B) The spectral shift of resonance peak in light transmission is measured to quantify the amount of EVs captured on the nanopore surface. a.u., arbitrary unit. (C) Scanning electron micrographs show the periodically arranged nanopore array and EVs captured on the surface. Each nanohole has a diameter of 200 nm and a periodicity of 500 nm. Katherine S. Yang et al., Sci Transl Med 2017;9:eaal3226 Published by AAAS