Synapse.

Slides:



Advertisements
Similar presentations
Synapses and neurotransmitters
Advertisements

What about communication between neurons?.  presynaptic ending – ◦ portion of the axon conveying information to the next neuron.
Neuronal Transmission
Neurotransmitters Chemicals that influence the firing of nerve cells Can “excite”-make firing more likely Or “inhibit” make firing less likely.
Signal transmission at synapses Alice Skoumalová.
Neurotransmitters Many Neurotransmitters (NT) exist: -Dopamine -Adrenaline -Serotonin -Acetylcholine Drugs can either: –Increase the effect of certain.
Synaptic Transmission Chapter 4 Pages Chemical Synapses  Most synapses in the brain are chemical. Electronically coupled gap junction synapses.
Part Fundamentals of Physiology Part II Food, Energy, and Temperature Part III Integrating systems Part IV Movement and Muscle Part V Oxygen, Carbon dioxide,
Synaptic Nerve Transmission Getting the Message From Here to There.
Neurotransmitters I The Life Cycle of a Conventional NT Biosynthesis & Storage Release Receptor Action Inactivation.
Boğaziçi University SCIENCE 102: Neurons and Synapses Prof.Dr. Hale Saybaşılı (BM501 Biology of Living Systems) Yrd.Doç.Dr. Burak Güçlü (BM502 Intro. to.
Synapses Figure
Widely Found and Studied Neurotransmitters  Glutamate – has excitatory functions  4 Ascending activating systems are very important  Cholinergic System.
NEURAL TRANSMISSION Neurons Electrical and Chemical Transmission.
DAVID SANTUCCI QUANTITATIVE BIOLOGY BOOTCAMP 2009 A BRIEF HISTORY OF THE SYNAPSE.
Chapter 5 Synaptic Transmission
Neuron & Synapse Quiz SBI 4UI Mrs. Tuma. 1. What part of the neuron receives messages from other neurons? (a) axon (b) myelin (c) dendrite (d) Schwann.
PTP 512 Neuroscience in Physical Therapy Introduction Neurotransmitters Min H. Huang, PT, PhD, NCS.
Additional review Neural synapse Neurotransmitters
University of Jordan1 Physiology of Synapses in the CNS- L2-L4 Faisal I. Mohammed, MD, PhD.
Questions 17-1 Q: What happens to a nerve impulse once it reaches the end of an axon? Q: How does one neuron communicate with another?
Neuron Used for communication between body parts May be as long as a meter.
Neurotransmitters Lecture 13.
Neurotransmitters: Catecholamines & Acetylcholine Chapters 5 & 6
Functional Human Physiology for the Exercise and Sport Sciences Synaptic Transmission and Neural Integration Jennifer L. Doherty, MS, ATC Department of.
Neurotransmitters & Receptors. Sensory neuron Motor neuron Receptor potentialAction potential Synaptic potential Action potential.
1 Synaptic Transmission. 2 Synaptic contacts Axodendritic – axon to dendrite Axodendritic – axon to dendrite Axosomatic – axon to soma Axosomatic – axon.
Neurotransmitters Lesson 13. Neurotransmitters n Chemical messengers l Signal between cells n Released at axon terminal l By action potentials n Metabolism.
NEURONS & NEURAL TRANSMISSION NEUROCHEMICAL MECHANISMS OF DRUG ACTION
Psych 181: Dr. Anagnostaras Lecture 5 Synaptic Transmission.
Synaptic Transmission How a neuron communicates with another neuron and the effects of drugs on this process. Types of Neurotransmitters.
Neurotransmitters Chemical communicators. Two basic kinds of Neurotransmitters Excitatory: – create Excitatory postsynaptic potentials: EPSP's – stimulate.
Neural Tissue: 2.
Copyright © 2004 Pearson Education, Inc., publishing as Benjamin Cummings The Synapse Key Stage 5 Biology.
Neurons: Cellular and Network Properties
Neurotransmitters A. Criteria 1. must mimic presynaptic effects if administered exogenously 2. must be released during activity of presynaptic neuron 3.
Read page on drugs and the brain What 3 major concepts should we study to understand this article further?
CBNS 106 Review Lecture 2.
Neural transmission. The Reticular theory vs the Synaptic theory.
Neurophysiology II: The Synapse Synapse Defined Space between adjacent neurons! Relays information from one neuron to another! Neuron  Neuron Neuron.
Quiz, quiz, trade 1.Look back at the synapse and transmission of a nerve impulse sequence. 2.Write a question you can answer on a piece of card (put the.
AP PSYCHOLOGY REVIEW Neuron Note #3. 1. Which part of the neuron receives messages from other cells? a) Axon b) Dendrite c) Soma d) Myelin e) Nucleus.
Synaptic Conduction What happens when an action potential reaches the axon terminals? Depends on the nature of “synapse” Synapse = special communication.
Synapse: Is a junction where a axon interacts with another neuron Presynaptic Terminal: End of the axon Postsynaptic Membrane: Membrane of the dendrite.
Tetraodotoxin (fish) Saxitoxin (dinoflagellate-red tide) -blocks sodium channels -75 deaths/year in Japan X more potent than cocaine -little bit.
Cell to cell communication in the nervous system The synapse Electrical synapse Chemical synapse Role of calcium “neurocrines” Receptors Post-synaptic.
Pharmacology of central Neurotransmitters Prof. Yieldez.
Neurotransmissions in the Central Nervous System Prof. Alhaider.
Psychology Drug Abuse. Psychology 3552 General Overview Problem of drug abuse Review of synaptic transmission Brain reward systems Mechanisms.
The Nervous System-Part II
The Nervous System-Part II Neurotransmitters, Drugs and Disease of the Brain.
Synaptic transmission
Acetylcholine & Other Neurotransmitters
Neurotransmitter Systems
M1 Spring April 8 00 AM Neurotransmitter Transporters
Structure of a Neuron: At the dendrite the incoming
Drugs affecting Neurotransmission
Chapter 7. Pharmacology and Biochemistry of Synaptic Transmission: Classical Transmitters Copyright © 2014 Elsevier Inc. All rights reserved.
What is the neural basis of behavior?
Neurotransmitters.
SYNAPSES AND DRUGS.
Neurons! Message = nerve impulse The impulse travels in one direction
12-7 Synapses Synaptic Activity Action potentials (nerve impulses)
SYNAPSES AND DRUGS.
Propagation of the action potential
SYNAPSES AND DRUGS.
Neurotransmission Across a Synapse
Neurotransmitters, reinforcement
Neurotransmitters and the Synapse
Cell to cell communication in the nervous system
Presentation transcript:

Synapse

Synapse

Electrical Synapse

Chemical Synapse

Electrical vs. Chemical

Synaptic vesicle

Synaptic vesicle

Synaptic vesicle

Synaptic cleft

Synaptic cleft

Some common neurotransmitters Action Receptors Acetylcholine (Ach) +/- Nicotinic, Muscarinic Norepinephrine (NE) + a1, a2, b1, b2 Dopamine (DA) +/- D1,D2 Glutamate (Glu) + NMDA, AMPA Serotonin (5-HT) +/- 5-HT1, etc GABA - GABA1, GABA2 Opioids (Enkephalin) - m,d,k

Neurotransmitter

Neurotransmitter

Glutamate receptor

Glutamate receptor

GABA receptor

GABA receptor

GABA receptor

Drug effects on receptor

Serotonin-Selective Reuptake Block

Postsynaptic potential

Long term potentiation

Long term potentiation

Long term potentiation

Long term depression

Synaptic inhibition

Neuromuscular junction

Postsynaptic response

Nicotinic receptor

Acetylcholine metabolism

Various receptors

Take home message