Horizontal gene transfer Maddalen Arizti Lopez de Aberasturi Genomics

Index Horizontal gene transfer Mechanisms Detection methods Importance of HGT Conclusion

Horizontal gene transfer (HGT) Transfer of genes between organisms in a manner other than traditional reproduction Acquisition of foreign genes  evolution of many organisms Organism Prokaryotes Eukaryotes

Mechanisms of HGT

Mechanisms of HGT

Detection methods Phylogenetic methods Phylogeny independent methods Codon-based approaches BLAST PCR-based approaches

Importance of HGT Adaptative advantages Bdelloid Rotifer Functional bacteria, plants and fungal genes Biochemistry improvements Evolution of eukaryotes Plantae  plastids Red algae  5% of coding genes Glaucophytes  400 genes Green plant Implications for medicine and biotechnology Important role in pathogenesis Therapeutic targets Antibiotic resistance  vaccines

Conclusion Study of mechanism in eukaryotes Evolutionary potential in all the organism More frequent in eukaryotes than we though Importance for medicine and new therapies

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