EASL Clinical Practical Guidelines: Management of Alcoholic Liver Disease  European Association for the Study of the Liver  Journal of Hepatology  Volume 57, Issue 2, Pages 399-420 (August 2012) DOI: 10.1016/j.jhep.2012.04.004 Copyright © 2012 European Association for the Study of the Liver Terms and Conditions

Fig. 1 Natural history of alcoholic liver disease (ALD). The spectrum of ALD is comprised of steatosis, steatohepatitis, fibrosis, cirrhosis, and superimposed hepatocellular carcinoma. Both environmental and genetic factors are known to modify the progression of ALD (adapted from [2] with permission from the American Gastroenterological Association). Journal of Hepatology 2012 57, 399-420DOI: (10.1016/j.jhep.2012.04.004) Copyright © 2012 European Association for the Study of the Liver Terms and Conditions

Fig. 2 Therapeutic algorithm for the treatment of patients with alcoholic steatohepatitis (ASH). ∗A Lille score ⩾0.45 indicating non-response and increased risks of infection and death. In non responders, the interruption of corticosteroids is recommended particularly in those classified as null responders (Lille score >0.56). Journal of Hepatology 2012 57, 399-420DOI: (10.1016/j.jhep.2012.04.004) Copyright © 2012 European Association for the Study of the Liver Terms and Conditions