Fig. 3. Frequencies of amino acids at critical PGT121 and 10-1074 contact sites in the SHIV-SF162P3 challenge stock. Frequencies of amino acids at critical.

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Presentation transcript:

Fig. 3. Frequencies of amino acids at critical PGT121 and 10-1074 contact sites in the SHIV-SF162P3 challenge stock. Frequencies of amino acids at critical PGT121 and 10-1074 contact sites in the SHIV-SF162P3 challenge stock. (A) “O” indicates an Asn that is part of a PNGS (positions 295, 301, and 332). The critical N332 and S334 residues are circled in red. aa, amino acid. (B) PGT121 and 10-1074 neutralization potency of SHIV-SF162P3 (wild-type) and SHIV-SF162P3 containing an N332A mutation. Boris Julg et al., Sci Transl Med 2017;9:eaao4235 Published by AAAS