Calorie Restriction à Lamarck

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Calorie Restriction à Lamarck Eugene V. Koonin Cell Volume 158, Issue 2, Pages 237-238 (July 2014) DOI: 10.1016/j.cell.2014.07.004 Copyright © 2014 Elsevier Inc. Terms and Conditions

Figure 1 The Epigenetic versus Genetic Routes of Lamarckian Evolution (A) The genetic mechanism. This route of Lamarckian evolution is illustrated using the case of the CRISPR-cas system. R, repeat; S, spacer (denoted protospacer in foreign DNA). The insertion of a new spacer is accompanied by repeat duplication. Cas1-Cas2, complex of two Cas protein that is involved in the excision of the protospacer from the foreign DNA and its insertion between repeats at the end of the CRISPR cassette. (B) The epigenetic mechanism. Assimilation is denoted by a broken arrow to emphasize that this is not a well-characterized process. Cell 2014 158, 237-238DOI: (10.1016/j.cell.2014.07.004) Copyright © 2014 Elsevier Inc. Terms and Conditions