PH-Stat Versus α-Stat Acid–Base Management Strategy During Hypothermic Circulatory Arrest Combined With Embolic Brain Injury Sebastian Dahlbacka, MS,

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Presentation transcript:

pH-Stat Versus α-Stat Acid–Base Management Strategy During Hypothermic Circulatory Arrest Combined With Embolic Brain Injury Sebastian Dahlbacka, MS, Janne Heikkinen, MS, Timo Kaakinen, MS, Päivi Laurila, MD, PhD, Vilho Vainionpää, MD, PhD, Kai Kiviluoma, MD, PhD, Timo Salomäki, MD, PhD, Hannu Tuominen, MD, PhD, Pasi Ohtonen, MS, Fausto Biancari, MD, PhD, Pasi Lepola, MS, Tatu Juvonen, MD, PhD The Annals of Thoracic Surgery Volume 79, Issue 4, Pages 1316-1325 (April 2005) DOI: 10.1016/j.athoracsur.2004.09.022 Copyright © 2005 The Society of Thoracic Surgeons Terms and Conditions

Fig 1 Postoperative behavioral outcome in the study groups. The Annals of Thoracic Surgery 2005 79, 1316-1325DOI: (10.1016/j.athoracsur.2004.09.022) Copyright © 2005 The Society of Thoracic Surgeons Terms and Conditions

Fig 2 Hemodynamic variables and brain oxygen partial pressure in the study groups. (Top left) Vascular resistance. (Top right) Mean arterial pressure. (Bottom left) Flow rate. (Bottom right) Brain oxygen partial pressure. *p value between study groups < 0.05. Values are expressed as the median with 25th and 75th interquartile range. (h = hours; m = minutes.) The Annals of Thoracic Surgery 2005 79, 1316-1325DOI: (10.1016/j.athoracsur.2004.09.022) Copyright © 2005 The Society of Thoracic Surgeons Terms and Conditions

Fig 3 Intracranial variables in the study groups. (Top left) Brain glucose. (Top right) Brain lactate/glucose ratio. (Bottom left) Intracranial pressure. (Bottom right) Brain lactate/pyruvate ratio. *p value between study groups < 0.05. Values are expressed as the median with 25th and 75th interquartile range. (HCA = hypothermic circulatory arrest; h = hours; min = minutes.) The Annals of Thoracic Surgery 2005 79, 1316-1325DOI: (10.1016/j.athoracsur.2004.09.022) Copyright © 2005 The Society of Thoracic Surgeons Terms and Conditions