Improved Patient Outcomes Best Available Clinical Evidence Patient’s

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Presentation transcript:

Improved Patient Outcomes Best Available Clinical Evidence Patient’s Values & Expectations Individual Clinical Expertise

Hierarchy of Evidence Strength of Evidence

1 Ask Questions 5 Evaluate 2 Search 4 Implement 3 Critically Appraise

Cause Effect / Outcome Other Factor Independent Variable Effect / Outcome Dependent Variable Other Factor Confounding Variable

Experimental Significance Practical Statistical Significance “Are the effects observed due to the changing levels of the factors real or due to random change?” Practical Significance “If a factor does have a statistically significant effect, then is the degree of effect practically useful given what we are trying to accomplish?”

Reliable Not Valid Low Validity Low Reliability Not Reliable Not Valid Reliable Valid

Measures of Central Tendency Mean, Median, Mode Mode Median Mean Measures of Central Tendency

Standard Deviation G = 68% G + B = 95% G + B + R = 99% 34% 34% 13.6% 2.15% 2.15% Standard Deviation

Patients Randomization Conditions 1 2 3 4 5 6 7 8 9 10