A. W. A. Baltzer, M. D. , C. Moser, M. D. , S. A. Jansen, M. D. , R

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Presentation transcript:

Autologous conditioned serum (Orthokine) is an effective treatment for knee osteoarthritis A.W.A. Baltzer, M.D., C. Moser, M.D., S.A. Jansen, M.D., R. Krauspe, M.D. Osteoarthritis and Cartilage Volume 17, Issue 2, Pages 152-160 (February 2009) DOI: 10.1016/j.joca.2008.06.014 Copyright © 2008 Osteoarthritis Research Society International Terms and Conditions

Fig. 1 Patient disposition. Flow chart showing screening and inclusion of patients. Osteoarthritis and Cartilage 2009 17, 152-160DOI: (10.1016/j.joca.2008.06.014) Copyright © 2008 Osteoarthritis Research Society International Terms and Conditions

Fig. 2 WOMAC scores (0–10 scale) as a function of time and treatment group 2 years after the last trial injections. (a) Valid-for-efficacy-population (N=188): patients who did not receive subsequent pharmacological or surgical treatment for OA (ACS: N=76; HA: N=56; saline: N=56). Figure shows mean±SE. *P<0.05 for the comparison ACS vs HA and saline; ‡P>0.05 for the comparison HA vs saline. (b) Intention-to-treat (LOCF) population (N=310): overall cohort with last value carried forward in patients who received subsequent therapies. Figure shows mean±SE. *P<0.05 for the comparison ACS vs HA and saline; ‡P>0.05 for the comparison HA vs saline. Osteoarthritis and Cartilage 2009 17, 152-160DOI: (10.1016/j.joca.2008.06.014) Copyright © 2008 Osteoarthritis Research Society International Terms and Conditions