Volume 5, Issue 3, Pages (March 2018)

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Volume 5, Issue 3, Pages 203-216 (March 2018) Effectiveness of systemic family therapy versus treatment as usual for young people after self-harm: a pragmatic, phase 3, multicentre, randomised controlled trial Prof David J Cottrell, FRCpsych, Alexandra Wright-Hughes, MSc, Michelle Collinson, MSc, Paula Boston, MSW, Prof Ivan Eisler, PhD, Sarah Fortune, PhD, Elizabeth H Graham, BA, Prof Jonathon Green, FRCPsych, Prof Allan O House, DM, Prof Michael Kerfoot, PhD, David W Owens, MD, Eirini-Christina Saloniki, PhD, Mima Simic, MD, Fiona Lambert, PGDip, Justine Rothwell, PhD, Sandy Tubeuf, PhD, Prof Amanda J Farrin, MSc The Lancet Psychiatry Volume 5, Issue 3, Pages 203-216 (March 2018) DOI: 10.1016/S2215-0366(18)30058-0 Copyright © 2018 The Author(s). Published by Elsevier Ltd. This is an Open Access article under the CC BY 4.0 license Terms and Conditions

Figure 1 Trial profile A full list of reasons for dropouts at each stage of the study is provided in the appendix. SHIFT=Self-Harm Intervention: Family Therapy. *Data was not obtained for these people because clinical services did not fill in forms or contact was lost. †Reasons for loss to follow-up were unable to contact, contacted but unable to arrange visit, withdrawal from researcher visits, and visit arranged but cancelled or no one home. The Lancet Psychiatry 2018 5, 203-216DOI: (10.1016/S2215-0366(18)30058-0) Copyright © 2018 The Author(s). Published by Elsevier Ltd. This is an Open Access article under the CC BY 4.0 license Terms and Conditions

Figure 2 Kaplan-Meier plot of time to self-harm Bars show 95% CI. The Lancet Psychiatry 2018 5, 203-216DOI: (10.1016/S2215-0366(18)30058-0) Copyright © 2018 The Author(s). Published by Elsevier Ltd. This is an Open Access article under the CC BY 4.0 license Terms and Conditions

Figure 3 Moderator analysis: hazard ratio for risk of hospital attendance due to repeat self-harm (A) Baseline young-person ICU unemotional subscale score (range 0–15). Higher scores indicate more unemotional traits. (B) Baseline caregiver FAD affective involvement subscale score (range 1–4). Higher scores indicate poorer family functioning. FAD=Family Assessment Device. ICU=Inventory of Callous Unemotional Traits. The Lancet Psychiatry 2018 5, 203-216DOI: (10.1016/S2215-0366(18)30058-0) Copyright © 2018 The Author(s). Published by Elsevier Ltd. This is an Open Access article under the CC BY 4.0 license Terms and Conditions