1. Volume 392, Issue 10156, Pages 1403-1412 (October 2018)
Efficacy and cost-effectiveness of nurse-led care involving education and engagement of patients and a treat-to-target urate-lowering strategy versus usual care for gout: a randomised controlled trial 
Prof Michael Doherty, MD, Wendy Jenkins, RGN, Helen Richardson, BA, Aliya Sarmanova, PhD, Abhishek Abhishek, PhD, Deborah Ashton, RGN, Christine Barclay, RGN, Sally Doherty, RGN, Prof Lelia Duley, MD, Rachael Hatton, MSc, Frances Rees, PhD, Prof Matthew Stevenson, PhD, Prof Weiya Zhang, PhD 
The Lancet 
Volume 392, Issue 10156, Pages (October 2018)
DOI: /S (18)
Copyright © 2018 The Author(s). Published by Elsevier Ltd. This is an Open Access article under the CC BY-NC-ND 4.0 licence Terms and Conditions

2. Figure 1
Trial profile
ITT=intention-to-treat. GP=general practitioner. *Patients with a diagnosis of gout who had had at least one gout flare in the previous 12 months. †Unable to commit time, poor health, gout flare more 12 months previously, advised by surgery not to contact, initial appointment was booked but cancelled and could not be rearranged.
The Lancet  , DOI: ( /S (18) )
Copyright © 2018 The Author(s). Published by Elsevier Ltd. This is an Open Access article under the CC BY-NC-ND 4.0 licence Terms and Conditions

3. Figure 2 Mean (95% CI) serum urate concentrations throughout the study
Data in the usual-care group were only available at baseline, 1 year, and 2 years but serum urate monitoring data recorded in follow-up visits were available in the nurse-led group.
The Lancet  , DOI: ( /S (18) )
Copyright © 2018 The Author(s). Published by Elsevier Ltd. This is an Open Access article under the CC BY-NC-ND 4.0 licence Terms and Conditions

4. Figure 3
Serum urate concentration, number of flares and presence of tophi at baseline, 1 year, and 2 years
(A) Mean (95% CI) serum urate concentration. (B) Mean (95% CI) number of flares. (C) Proportion of patients with any tophi.
The Lancet  , DOI: ( /S (18) )
Copyright © 2018 The Author(s). Published by Elsevier Ltd. This is an Open Access article under the CC BY-NC-ND 4.0 licence Terms and Conditions