Prokaryotic Development: A New Player on the Cell Cycle Circuit

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Prokaryotic Development: A New Player on the Cell Cycle Circuit Craig Stephens  Current Biology  Volume 14, Issue 13, Pages R505-R507 (July 2004) DOI: 10.1016/j.cub.2004.06.038

Figure 1 The Caulobacter crescentus cell cycle and the GcrA/CtrA circuit. (A) The Caulobacter cell cycle, beginning with the motile swarmer cell. Oscillation of CtrA and GcrA protein levels through the cell cycle is shown underneath [2]. (B) The GcrA/CtrA regulatory circuit. The gcrA and ctrA genes are shown as boxes, with promoters to the left and small arrows indicating transcription start sites. The GcrA and CtrA protein products are shown in blue and red, respectively. CtrA activation requires phosphorylation (P) by the CckA kinase. Current Biology 2004 14, R505-R507DOI: (10.1016/j.cub.2004.06.038)