Transcriptional response to mating in whole A. gambiae females.

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Transcriptional response to mating in whole A. gambiae females. Transcriptional response to mating in whole A. gambiae females. (A) Agglomerative cluster using cosine correlation-based similarity of 141 genes exhibiting a >2-fold change in expression at 2 h, 6 h, and 24 h after mating. Each gene is represented by a vertical line. Expression relative to virgins is indicated by a color gradient (see bar). (B) Functional classes of the 141 genes. The number of genes up-regulated (Left) and down-regulated (Right) at each time point are specified in the arrows. Pie charts indicate the proportion of up-regulated (Left) and down-regulated (Right) genes at each time point that belong to each functional category. Genes involved in cell cycle regulation have been included in the “nucleic acid binding” group. David W. Rogers et al. PNAS 2008;105:49:19390-19395 ©2008 by National Academy of Sciences