a-d) Typical changes over time in different diffuse lung diseases

Slides:



Advertisements
Similar presentations
HRCT of Common Lung Diseases W. Richard Webb MD. Common Lung Diseases: HRCT Infections (pneumonia, airways disease) Infections (pneumonia, airways disease)
Advertisements

High-Resolution Lung CT: Key Findings and What They Mean W
INTERSTITIAL LUNG DISEASE
Esam H. Alhamad, M.D Assistant Professor of Medicine Consultant Pulmonary & Critical Care Medicine.
History : 52-year-old male presented with a left testicular mass. An initial chest radiograph was performed, followed by a CT. Question : What are the.
Figure 1. Proposed mechanisms in the pathogenesis of hypersensitivity pneumonitis. exaggerated immune reaction activation of the fibroblast accumulation.
Case of the Month 25 July 2017 History:
Figure 1. The three stages of humidifier disinfectant-associated lung injury in a 33-year-old woman. (A) Initial computed tomography (CT) scan shows diffuse.
Fig. 1. Abnormalities on chest imaging of the patient
Diagnostic Approach to the Patient With Diffuse Lung Disease
Kaplan–Meier survival curves of interstitial pneumonia with autoimmune features (IPAF) with usual interstitial pneumonia (UIP) pattern (on high-resolution.
Changes in high-resolution computed tomography (HRCT) pattern over time. a) Idiopathic pulmonary fibrosis (IPF), increased specificity over time. Changes.
Longitudinal imaging after initial diagnosis
High-resolution computed tomography (HRCT) features of interstitial lung abnormalities. a) HRCT of a 56-year-old patient whose mother died of idiopathic.
Radiology assessment of pulmonary amyloidosis
The Risk of Cytotoxic Chemotherapy-Related Exacerbation of Interstitial Lung Disease with Lung Cancer  Hirotsugu Kenmotsu, MD, Tateaki Naito, MD, Madoka.
Serial high-resolution computed tomography (HRCT) scans at the lung window from patient 4, who was treated with cladribine for progressive multisystem.
High-resolution chest computed tomography images of a patient with lymphangioleiomyomatosis, showing round-shaped, thin-walled cysts distributed diffusely.
High-resolution computed tomography scan revealing a nonspecific interstitial pneumonia pattern with basal predominant ground-glass opacities and associated.
Imaging and histological correlation in lung adenocarcinoma classification. a) Computed tomography (CT) scan demonstrating a solid attenuation nodule.
a) Chest radiograph showing bilateral coarse interstitial shadowing
Nonspecific interstitial pneumonia in a woman a, c) at the time of Sjögren's syndrome diagnosis and b) after 3 years. a, b) High-resolution computed tomography.
A) Usual interstitial pneumonia in a 69-year-old woman with primary Sjögren's syndrome. a) Usual interstitial pneumonia in a 69-year-old woman with primary.
Axial computed tomography (CT) images a) at baseline and b) at a 12-month follow-up scan, in a patient with idiopathic pulmonary fibrosis (IPF). b) Note.
Extent of interstitial lung disease (ILD) in patients with systemic sclerosis-associated ILD. A simple stratification that utilises pulmonary function.
A–c) This lung biopsy from a 55-year-old male patient, who was a nonsmoker, shows a typical desquamative interstitial pneumonia pattern. a–c) This lung.
Diagnosis of Interstitial Lung Diseases
Rubinowitz Ami N. , MD, Moon Marianne , MD, Homer Robert , MD, PhD 
Coronal chest computed tomography scan showing multiple areas of central ground-glass opacity, surrounded by ring or crescentic-shape, dense air-space.
Serial computed tomography (CT) imaging for monitoring disease progression in patients with idiopathic pulmonary fibrosis. Serial computed tomography (CT)
Electromagnetic navigation image: the icon representing the locatable guide (arrow) can be seen 3 mm away from the centre of a small pulmonary nodule in.
Smoking-related fibrosis with dense acellular fibrosis that frequently surrounds cystic emphysematous spaces, both in a) centrilobular (haematoxylin and.
Nonspecific interstitial pneumonia: high-resolution computed tomography images from a 46-year-old male patient who underwent lung transplantation. a) The.
Typical computed tomography features of acute respiratory distress syndrome showing: non-homogeneous distribution, a ventro-dorsal gradient of density,
Radiodiagnostic imaging
Evaluation by high-resolution computed tomography (HRCT).
Serial high-resolution computed tomography (HRCT) scans at the lung window from patient 2, who developed several episodes of right pneumothorax that required.
Forest plots of the correlation between high-resolution computed tomography (HRCT) scores and pulmonary function test values. Forest plots of the correlation.
Pattern high-resolution computed tomography consistent with nonspecific interstitial pneumonia in a patient with histological diagnosis of usual interstitial.
Evaluation of acute symptoms
A summary of the pathogenesis, pathophysiology and clinical implications of the pulmonary vascular and cardiac abnormalities in interstitial lung disease.
A) Respiratory bronchiolitis: the intra-alveolar accumulation of finely pigmented macrophages (smoker’s macrophages) (haematoxylin and eosin, 400×). a)
Time to disease progression or death in a) the whole Bosentan Use in Interstitial Lung Disease (BUILD)-1 study population and b) the subpopulation with.
Evaluation of complications.
Simplified diagram of the multidisciplinary process to diagnose interstitial lung disease, including a clinician, radiologist, pathologist and also a geneticist:
High-resolution computed tomography scan of a 59-year-old female patient with undifferentiated connective tissue disease, showing patterns of nonspecific.
A) High-resolution computed tomography shows innumerable ill-defined centrilobular ground-glass opacity nodules, characteristic of sub-acute hypersensitivity.
Representative images of computed tomography (CT) scans in patients with small airways disease. a) An inspiratory CT scan in a patient with hypersensitivity.
Transbronchial cryobiopsy (TBCx)
A: Computed tomogram shows bilateral dependent consolidation in a patient with ARDS, as well as ground-glass opacities in the non-dependent lung. A: Computed.
A) Positron emission tomography scan showing 18F-fluorodeoxyglucose uptake in the right supraclavicular, hilar and mediastinal lymph nodes and in the left.
Example of thin parenchymal section computed tomography findings in desquamative interstitial pneumonia: patchy ground-glass attenuation with a peripheral.
Chronic hypersensitivity pneumonitis with usual interstitial pneumonia pattern. a) At low magnification, bronchiolar damage with bridging fibrosis between.
A) Axial and b) coronal computed tomography scans of usual interstitial pneumonia pattern in a patient with rheumatoid arthritis. a) Axial and b) coronal.
High-resolution computed tomography with nonspecific interstitial pneumonia pattern in a patient with connective tissue disease; bilateral reticulation.
Use of high-resolution computed tomography imaging to diagnose different connective tissue disease-associated interstitial lung diseases (ILDs), and to.
A) High-resolution computed tomography (HRCT) scan of the chest at the lung window level from patient 1 showing a characteristic nodulocystic pattern at.
Procedure for the diagnosis of interstitial lung diseases.
a) A 2-year-old male with Niemann–Pick disease type A
High-resolution computed tomography from a patient with anti-Jo1 positive polymyositis showing basilar predominate reticulation and ground-glass opacity.
Left upper lobe complete atelectasis 2 days after implantation of four endobronchial valves into the left upper lobe in a patient with emphysema. a) Chest.
Thoracic high-resolution computed tomography: predominant diffuse ground-glass opacities associated with a lymphatic distribution of micronodules with.
High-resolution computed tomography scan demonstrating a typical example of usual interstitial pneumonia pattern with honeycombing change and traction.
Imaging and histological correlation in lung adenocarcinoma classification. a) Computed tomography (CT) scan demonstrating a ground-glass nodule that on.
Diagnostic algorithm for idiopathic pulmonary fibrosis (IPF).
High-resolution computed tomography images of smoking-related interstitial lung diseases (ILDs). a) Pulmonary Langerhans cell histiocytosis, b) respiratory.
High-resolution computed tomography (HRCT) images from a 75-year-old, male ex-smoker with combined pulmonary fibrosis and emphysema syndrome (CPFE). a)
Chest high-resolution computed tomography (HRCT) of a–c) acute hypersensitivity pneumonitis and d–f) chronic hypersensitivity pneumonitis. Chest high-resolution.
A) Mucosa-associated lymphoid tissue lymphoma in a 45-year-old woman with primary Sjögren's syndrome. a) Mucosa-associated lymphoid tissue lymphoma in.
A) Smokers’ macrophages show a fine, golden haemosiderin cytoplasmic pigment; b) in respiratory bronchiolitis (RB), smokers’ macrophages are located in.
Presentation transcript:

a-d) Typical changes over time in different diffuse lung diseases a-d) Typical changes over time in different diffuse lung diseases. a) Subacute hypersensitivity pneumonitis: baseline (left) and 6-month follow-up (right) high-resolution computed tomography (HRCT). a-d) Typical changes over time in different diffuse lung diseases. a) Subacute hypersensitivity pneumonitis: baseline (left) and 6-month follow-up (right) high-resolution computed tomography (HRCT). Ground glass opacity and centrilobular nodules demonstrate significant interval decrease after antigen removal with mild persistent abnormality remaining including reticulation. b) Desquamative interstitial pneumonia: baseline (left) and 3-year follow-up (right) HRCT. Subpleural ground glass opacity seen on the baseline HRCT has evolved into cystic lucencies in a patient who continued to smoke. The cystic lucencies may represent emphysema surrounded by fibrosis. c) Sarcoidosis: baseline (left) and 4-year follow-up (right) HRCT. Perilymphatic nodules on the initial HRCT evolve into fibrosis as evidenced by reticulation, architectural distortion, and mild bronchiectasis. d) Organising pneumonia: baseline (left) and 2-year follow-up (right) HRCT. Ground glass opacity, consolidation, and the reversed halo sign on the initial HRCT evolves to fibrosis after treatment with corticosteroids. Brett M. Elicker et al. Eur Respir Rev 2017;26:170008 ©2017 by European Respiratory Society