You Got to Know When to Hold (or Unfold) ‘Em…

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You Got to Know When to Hold (or Unfold) ‘Em… Daniel N. Hebert, Kshama D. Chandrasekhar, Lila M. Gierasch Molecular Cell Volume 48, Issue 1, Pages 3-4 (October 2012) DOI: 10.1016/j.molcel.2012.09.022 Copyright © 2012 Elsevier Inc. Terms and Conditions

Figure 1 The Sphere of Influence of the Ribosome and TF on the Nascent Chain The translating ribosome (dark purple structure) influences the conformational freedom of the nascent polypeptide (blue sinuous line) up to 100 amino acids in length from the ribosomal P site (light purple shading). Once a nascent chain reaches a length of greater than 100 amino acids, TF can hold or unfold it (pink shading). The ruler denotes amino acid chain length. Molecular Cell 2012 48, 3-4DOI: (10.1016/j.molcel.2012.09.022) Copyright © 2012 Elsevier Inc. Terms and Conditions