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Mitochondria and Cancer

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Presentation on theme: "Mitochondria and Cancer"— Presentation transcript:

1 Mitochondria and Cancer
Wei-Xing Zong, Joshua D. Rabinowitz, Eileen White  Molecular Cell  Volume 61, Issue 5, Pages (March 2016) DOI: /j.molcel Copyright © 2016 Elsevier Inc. Terms and Conditions

2 Figure 1 Mitochondria as Biosynthetic and Signaling Hubs
The TCA cycle uses substrates from glycolysis, fatty acid oxidation, and amino acid catabolism to generate building blocks and high-energy electrons (NADH and FADH2) to power the ETC. Major biosynthetic products produced by mitochondria and signaling pathways regulated by mitochondrial function are indicated. Molecular Cell  , DOI: ( /j.molcel ) Copyright © 2016 Elsevier Inc. Terms and Conditions

3 Figure 2 Characteristics of Oncocytic Tumors with Functional versus Defective Mitochondria Molecular Cell  , DOI: ( /j.molcel ) Copyright © 2016 Elsevier Inc. Terms and Conditions

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