AND THE EARTH HATH HE APPOINTED FOR HIS CREATURES

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And the earth hath He appointed for His creatures. wherein are fruit and sheathed palm trees.husked grain and scented herb. which is it of the favours.
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Presentation transcript:

AND THE EARTH HATH HE APPOINTED FOR HIS CREATURES AND THE EARTH HATH HE APPOINTED FOR HIS CREATURES. WHEREIN ARE FRUIT AND SHEATHED PALM TREES.HUSKED GRAIN AND SCENTED HERB. WHICH IS IT OF THE FAVOURS OF YOUR LORD THAT YE DENY? 11-13 Al Rahman Al Quran 12/1/2018 Dr Jariya Wajahat

DIGESTION AND ABSORPTION LIPIDS DIGESTION AND ABSORPTION 12/1/2018 Dr Jariya Wajahat

DIETARY LIPIDS 1.TRIGLYCERIDES 2.CHOLESTEROL 3.CHOLESTEROL ESTERS 4.PHOSPHOLIPIDS 12/1/2018 Dr Jariya Wajahat

DIGESTION OF LIPIDS ENZYMES EMULSIFICATION LIPASES ( Hydrolyze FA from Triglycerides ) Chain Lengh pH EMULSIFICATION BILE SALTS 12/1/2018 Dr Jariya Wajahat

Short and Medium Chain FA LIPASES LINGUAL GASTRIC Short and Medium Chain FA 12/1/2018 Dr Jariya Wajahat

PANCREATIC ENZYMES PANCREATIC LIPASE COLIPASE CHOLESTEROL ESTERASE PHOSPHOLIPASE A2 LYSOPHOSPHOLIPASE 12/1/2018 Dr Jariya Wajahat

LIPASES cont. PANCREATIC LIPASE COLIPASE (Activated by Trypsin) FA OF ALL CHAIN LENGTHS POSITION 1 & 3 OF TG PRODUCING FREE FA & 2 MAG 12/1/2018 Dr Jariya Wajahat

CONTROL OF LIPID DIGESTION CHOLECYSTOKININ SECRETIN 12/1/2018 Dr Jariya Wajahat

2 MONOACYLGLYCEROL TRIACYLGLYCEROL 12/1/2018 Dr Jariya Wajahat

CHOLESTEROL ESTERASE (Requires bile salts) 12/1/2018 Dr Jariya Wajahat

PHOSPHOLIPASE A2 PHOSPHOLIPID LYSOPHOSPHOLIPID Activated by trypsin Requires bile salts PHOSPHOLIPID LYSOPHOSPHOLIPID 12/1/2018 Dr Jariya Wajahat

LYSOPHOSPHOLIPASE LYSOPHOSPHOLIPID GLCERYLPHOSPHORYL BASE 12/1/2018 Dr Jariya Wajahat

( hydrophobic and hydrophilic) CCK Pancreatic enzymes Contraction of gall bladder BILE SALTS ( hydrophobic and hydrophilic) 12/1/2018 Dr Jariya Wajahat

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Lipid digestion/absorption CLINICAL ASPECTS Lipid digestion/absorption ALCOHOL EXCESS OBSTRUCTIVE JAUNDICE ABETALIPOPROTEINEMIA CYSTIC FIBROSIS 12/1/2018 Dr Jariya Wajahat

ALCOHOL EXCESS INFLAMMATORY PROCESS IN PANCREAS PROTEINACEOUS PLUGS IN SMALL PANCREATIC DUCTS BACK PRESSURE INJURY AUTODIGESTION OF ACINI 12/1/2018 Dr Jariya Wajahat

ALCOHOL EXCESS C/F Steatorrhea TREATMENT Commercial preparation of pancreatic enzymes Avoid alcohol 12/1/2018 Dr Jariya Wajahat

OBSTRUCTIVE JAUNDICE OBSTRUCTION OF COMMON BILE DUCT CHOLESTASIS DIETARY FATS NOT READILY EMULSIFIED & DIGESTED 12/1/2018 Dr Jariya Wajahat

OBSTRUCTIVE JAUNDICE C/F JAUNDICE CLAY COLORED STOOL DARK URINE FAT SOLUBLE VITAMIN DEFICIENCY 12/1/2018 Dr Jariya Wajahat

ABETALIPOPROTEINEMIA CANNOT FORM CHYLOMICRONS OR VLDL TG ACCUMULATE IN INTESTINAL & LIVER CELLS BLOOD LIPOPROTEINS LOW DEFICIENCY OF FAT SOL VITAMINS & ESSENTIAL FA 12/1/2018 Dr Jariya Wajahat

IN ABETALIPOPROTEINEMIA FOLLOWING IS NOT PRESENT IN BLOOD? HDL CHYLOMICRONS LDL 12/1/2018 Dr Jariya Wajahat

The end 12/1/2018 Dr Jariya Wajahat

EXCELLENT! 12/1/2018 Dr Jariya Wajahat

TRY AGAIN! 12/1/2018 Dr Jariya Wajahat

SORRY! 12/1/2018 Dr Jariya Wajahat

HUMAN VS COW’S MILK HUMAN COW’S LONG CHAIN POLYUNSATURATED FA IMPORTANT FOR BRAIN DEVELOPMENT PANCREATIC LIPASE & BILE SALTS LOW IN NEWBORN LINGUAL & GASTRIC LIPASES ACID STABLE LIPASE COW’S SHORT AND MEDIUM CHAIN FA DO NOT REQUIRE BILE SALTS NOT PACKAGED IN CHYLOMICRINS ENTER PORTAL BLOOD RATHER THAN LYMPH BOUND TO SERUM ALBUMIN 12/1/2018 Dr Jariya Wajahat