Relationship between Genotype and Phenotype

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Presentation transcript:

Relationship between Genotype and Phenotype Molecular Basis for Relationship between Genotype and Phenotype genotype DNA DNA sequence transcription RNA translation amino acid sequence protein function phenotype organism

Complementation Analysis Allelic Non-Allelic m1 m2 m1 m2 Cis Trans + + + + Wild-type Wild-type + m2 + m2 m1 + m1 + Mutant Wild-type Mutant alleles complement if wild-type phenotype results when two haploid genomes carrying different mutations are united in the same cell.

How many loci are represented here? Mutant I X Mutant II F1 a b c d e f o + + o o + a + o + + + + b + + o + + o c o + + o o + d o + + o o + e + + o + + o f