(A) Heat map showing expression changes during in vitro differentiation of nscs to astrocytes. (A) Heat map showing expression changes during in vitro.

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(A) Heat map showing expression changes during in vitro differentiation of nscs to astrocytes. (A) Heat map showing expression changes during in vitro differentiation of nscs to astrocytes. Results are shown for each cell line and day of differentiation. (B) Principal component analysis. In this constructed space, the λ1 component mainly associated with differentiation is shown to rise to near maximal levels by day 1 after induction of differentiation. Dataset S1 has a complete list of genes used in our study and their expression levels. Sergio Branciamore et al. PNAS 2018;115:44:E10379-E10386 ©2018 by National Academy of Sciences