PERMISSIONS COORDINATING CENTRE Scotland Hosted Multicentre Research APPLICANT PERMISSIONS COORDINATING CENTRE Submit IRAS Form(s) and study documentation to lead nation confirming participating sites. Once R&D permission is granted at each site authorisation has been granted to proceed with the study . Create and set-up study on IRAS, completing relevant forms. Using study checklist, compile study documentation for submission. Submit SSI Form(s) to relevant R&D office(s) to begin local review. Commercial research study? Full Document Set (FDS) available? 1 No Await outstanding documents from lead nation/commercial contact Receive application/documents from lead nation No Assign a reference number and Governance Reviewer Create study record on SReDA, select participating R&D offices. Yes Yes Request any remaining documents from commercial contact. Full governance review can run in parallel with other participating nations. Notify participating R&D offices of FDS and if applicable start Governance Review clock Upload documents to SReDA Completed Governance Report received from Scottish Governance Reviewer Upload Governance Report to SReDA notifying participating R&D offices. 1. Lead nation Governance Report is included in the FDS for non-commercial research. 1. Lead nation Governance Report is included in the FDS for non-commercial research studies.