A review of the preclinical and clinical data of newer intranasal steroids used in the treatment of allergic rhinitis William R. Lumry, MD Journal of.

Slides:

Advertisements

Similar presentations

The Inhaled Steroid Treatment As Regular Therapy in Early Asthma (START) study 5- year follow-up: Effectiveness of early intervention with budesonide in.

Advertisements

Tuomo Puhakka, MDa, Mika J

Oxymetazoline adds to the effectiveness of fluticasone furoate in the treatment of perennial allergic rhinitis Fuad M. Baroody, MD, David Brown, MD,

Efficacy and safety profile of fexofenadine HCL

Effect of 2-year placebo-controlled immunotherapy on airway symptoms and medication in patients with birch pollen allergy Monica B. Arvidsson, MD, Olle.

Twenty-four hour pattern in symptom intensity of viral and allergic rhinitis: Treatment implications Michael H. Smolensky, PhDa, Alain Reinberg, MDb,

Treatment effect of sublingual immunotherapy tablets and pharmacotherapies for seasonal and perennial allergic rhinitis: Pooled analyses Stephen R. Durham,

F.Estelle R. Simons, MDa, Bruce M. Prenner, MDb, Albert Finn, MDc

Treating acute rhinosinusitis: Comparing efficacy and safety of mometasone furoate nasal spray, amoxicillin, and placebo Eli O. Meltzer, MD, Claus Bachert,

David B Allen, MD Journal of Allergy and Clinical Immunology

Clinical outcomes and adverse effect monitoring in allergic rhinitis

Safety and efficacy of mometasone furoate aqueous nasal spray in children with allergic rhinitis: Results of recent clinical trials Javier Dibildox,

Treatment effect of sublingual immunotherapy tablets and pharmacotherapies for seasonal and perennial allergic rhinitis: Pooled analyses Stephen R. Durham,

Asthma diagnosis and treatment: Filling in the information gaps

Fluticasone furoate nasal spray: A single treatment option for the symptoms of seasonal allergic rhinitis Harold B. Kaiser, MD, Robert M. Naclerio, MD,

Eli O. Meltzer, MD, Michael S. Blaiss, MD, M

Fluticasone furoate nasal spray reduces the nasal-ocular reflex: A mechanism for the efficacy of topical steroids in controlling allergic eye symptoms

Comparison of once-daily ebastine 20 mg, ebastine 10 mg, loratadine 10 mg, and placebo in the treatment of seasonal allergic rhinitis Paul H. Ratner,

Bruce M. Prenner, MD, Bobby Q. Lanier, MD, David I

Safety and efficacy of mometasone furoate aqueous nasal spray in children with allergic rhinitis: Results of recent clinical trials Javier Dibildox,

Comparison of the efficacy of budesonide and fluticasone propionate aqueous nasal spray for once daily treatment of perennial allergic rhinitis James.

As-needed use of fluticasone propionate nasal spray reduces symptoms of seasonal allergic rhinitis Albert Jen, MD, Fuad Baroody, MD, Marcy de Tineo,

Efficacy and safety profile of fexofenadine HCL

Edwin A. Bronsky, MD, Howard Druce, MD, Steven R. Findlay, MD, Frank C

Use of ipratropium bromide nasal spray in chronic treatment of nonallergic perennial rhinitis, alone and in combination with other perennial rhinitis.

Harold B. Kaiser, MDa, Steven R. Findlay, MD†, John W

Comparison of a nasal glucocorticoid, antileukotriene, and a combination of antileukotriene and antihistamine in the treatment of seasonal allergic rhinitis

Oxymetazoline adds to the effectiveness of fluticasone furoate in the treatment of perennial allergic rhinitis Fuad M. Baroody, MD, David Brown, MD,

The impact of allergic rhinitis on bronchial asthma

Clinical outcomes and adverse effect monitoring in allergic rhinitis

Michael Mellon, MD Journal of Allergy and Clinical Immunology

Effect of intranasal azelastine and beclomethasone dipropionate on nasal symptoms, nasal cytology, and bronchial responsiveness to methacholine in allergic.

Peter König, MD, PhD Journal of Allergy and Clinical Immunology

H.William Kelly, PharmD Journal of Allergy and Clinical Immunology

A dose-ranging study of the efficacy and safety of azelastine nasal spray in the treatment of seasonal allergic rhinitis with an acute model John M.

A review of the current guidelines for allergic rhinitis and asthma

Fluticasone propionate aqueous nasal spray reduces inflammatory cells in unchallenged allergic nasal mucosa: Effects of single allergen challenge Adriaan.

News & Notes Journal of Allergy and Clinical Immunology

Quality of life in adults and children with allergic rhinitis

Efficacy of nebulized budesonide in treatment of severe infantile asthma: A double-blind study Jacques de Blic, MDa, Christophe Delacourt, MDa, Muriel.

Budesonide delivered by Turbuhaler is effective in a dose-dependent fashion when used in the treatment of adult patients with chronic asthma William.

Subjective and objective assessments in patients with seasonal allergic rhinitis: Effects of therapy with mometasone furoate nasal spray Eli O. Meltzer,

Peter S. Creticos, MD Journal of Allergy and Clinical Immunology

Clinical need for a nebulized corticosteroid

F.Estelle R. Simons, MDa, Bruce M. Prenner, MDb, Albert Finn, MDc

Model for outcomes assessment of antihistamine use for seasonal allergic rhinitis Robert P. Harvey, MD, Carolyn Comer, MD, Barbara Sanders, MD, Ross Westley,

Treating acute rhinosinusitis: Comparing efficacy and safety of mometasone furoate nasal spray, amoxicillin, and placebo Eli O. Meltzer, MD, Claus Bachert,

A comparison of multiple doses of fluticasone propionate and beclomethasone dipropionate in subjects with persistent asthma Gordon D. Raphael, MDa, Robert.

News & Notes Journal of Allergy and Clinical Immunology

Double-blind placebo-controlled evaluation of sublingual-swallow immunotherapy with standardized Parietaria judaica extract in children with allergic.

A placebo- and active-controlled randomized trial of prophylactic treatment of seasonal allergic rhinitis with mometasone furoate aqueous nasal spray

Low-dose inhaled fluticasone propionate versus oral zafirlukast in the treatment of persistent asthma Eugene R. Bleecker, MDa, Michael J. Welch, MDb,

Observations on emerging patterns of asthma in our society

The role and remediation of animal allergens in allergic diseases

Chemokines in seasonal allergic rhinitis

Bradykinin increases the in vivo expression of the CXC chemokine receptors CXCR1 and CXCR2 in patients with allergic rhinitis Jane Eddleston, PhD, Sandra.

Preparing patients and health professionals for the transition to chlorofluorocarbon-free inhalers: The British perspective Helen Donohoe, MSc (Econ)

Corticosteroids in the treatment of pediatric allergic rhinitis

Mometasone furoate administered once daily is as effective as twice-daily administration for treatment of mild-to-moderate persistent asthma James P.

An intranasal Syk-kinase inhibitor (R112) improves the symptoms of seasonal allergic rhinitis in a park environment Eli O. Meltzer, MD, Robert B. Berkowitz,

Determinants of systemic manifestations of food allergy

Abnormalities of cell and mediator levels in bronchoalveolar lavage fluid of patients with mild asthma Sally E. Wenzel, MD Journal of Allergy and Clinical.

Tuomo Puhakka, MDa, Mika J

10. Drug allergy Journal of Allergy and Clinical Immunology

Double-blind, placebo-controlled study comparing the efficacy and safety of fexofenadine hydrochloride (120 and 180 mg once daily) and cetirizine in seasonal.

The correlation between allergic rhinitis and sleep disturbance

Concomitant montelukast and loratadine as treatment for seasonal allergic rhinitis: A randomized, placebo-controlled clinical trial Eli O. Meltzer, MDa,

News & Notes Journal of Allergy and Clinical Immunology

An intranasal Syk-kinase inhibitor (R112) improves the symptoms of seasonal allergic rhinitis in a park environment Eli O. Meltzer, MD, Robert B. Berkowitz,

Clinical relevance of inhaled corticosteroids and HPA axis suppression

Presentation transcript:

A review of the preclinical and clinical data of newer intranasal steroids used in the treatment of allergic rhinitis William R. Lumry, MD Journal of Allergy and Clinical Immunology Volume 104, Issue 4, Pages s150-s159 (October 1999) DOI: 10.1016/S0091-6749(99)70311-8 Copyright © 1999 Mosby, Inc. Terms and Conditions

Fig. 1 Mometasone furoate nasal spray (MFNS) compared with beclomethasone dipropionate (BDP) in seasonal allergic rhinitis. Percentage of patients with no or mild symptoms by physician evaluation. Age ≥18 years. Asterisk, P < .05 compared with placebo vehicle control. NS, Not significant. (Adapted with permission from Hebert JR, Nolop K, Lutsky BN. Once-daily mometasone furoate aqueous nasal spray [Nasonex™] in seasonal allergic rhinitis: an active- and placebo-controlled study. Allergy 1996;51:569-76. ©1996 Munksgaard International Publishers Ltd., Copenhagen, Denmark.) Journal of Allergy and Clinical Immunology 1999 104, s150-s159DOI: (10.1016/S0091-6749(99)70311-8) Copyright © 1999 Mosby, Inc. Terms and Conditions

Fig. 2 Mometasone furoate nasal spray (MFNS) compared with fluticasone propionate in the treatment of perennial allergic rhinitis after 12 weeks of topical treatment. Percentage of patients with perennial rhinitis with complete or marked symptom relief after 12 weeks of treatment with mometasone furoate nasal spray (200 mg/day), fluticasone propionate (200 mg/day), or placebo. N = 550, age 12 to 77 years. (From Day J, Nolop K, Lutsky BN, I94-079 Study Group. Comparison of once-daily treatment with mometasone furoate [Nasonex™] and fluticasone propionate aqueous nasal sprays for the treatment of perennial rhinitis [abstract 1792]. J Allergy Clin Immunol 1997;99:S441.) Journal of Allergy and Clinical Immunology 1999 104, s150-s159DOI: (10.1016/S0091-6749(99)70311-8) Copyright © 1999 Mosby, Inc. Terms and Conditions