Slit-Robo Cancer Cell Volume 4, Issue 1, Pages 1-2 (July 2003)

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Slit-Robo Cancer Cell Volume 4, Issue 1, Pages 1-2 (July 2003) Zhao-Jun Liu, Meenhard Herlyn Cancer Cell Volume 4, Issue 1, Pages 1-2 (July 2003) DOI: 10.1016/S1535-6108(03)00166-1

Figure 1 Tumor induces angiogenesis through Slit-Robo signaling Tumor cells secrete the Slit2 protein which forms a gradient field for the attraction of endothelial cells through interaction with Robo1 on endothelial cell surfaces. Endothelial cells migrate toward tumor mass and form new blood vessels. Tumor and endothelial cells are represented by blue and red, respectively. Cancer Cell 2003 4, 1-2DOI: (10.1016/S1535-6108(03)00166-1)