BLOOD DONATION SELECTION CRITERIA AND SAFE ADMINSTRATION

MEASURES TO POTECT DONOR FROM ADVERSE EFFECTS

MEASURES TO PROTECT RECEPIENT

LABORARTORY TESTS ON BLOOD DONATIONS ABO and RhD grouping Screening for atypical red cell autoantibodies Women of child bearing age should be matched for c and K as anti c and anti K aremajor causes of HDN Requirements for blood for neonatal and intrauterine use,include useof repeat donors,HBS negative and exclusion of high titers ant A anti B

MICROBIAL TESTING IN ENGLAND AND NORTH WALES

TANSFUSION TRANSMISSABLE AGENTS

SAFE ADMINISTRATION OF BLOOD Patient identification Postive patient identification at all stages of tranfusion process “wrong blood in tube “(WBIT) can result in death…occurs due to human error… Detection and approach to transfusion reactions Baseline observations and regular monitoring… With tranfusion reaction patient may have: cadiovascular collaspe,anaphylaxis,TRALI and TACO

STEPS TO BE TAKEN IN CASE OF SERIOUS TRANSFUSION REACTION Stop and disconnect blood pack Maintain venous access with physiological saline,commence resuscitation if needed Take samples of blood for CBC,RFTs,LFTs,cultures,coagulation screen,repeat comatability testing,DAT,LDH,urine for Hb Check identification details of the patient Consider key additional features e.g. fever shock without anaphylaxis_ABO mismatched transfusion or bacterial sepsis;dispnea_TRALor TACO Check O saturation blood gases CXR Seek early support from critical care team