Exceptions to Basic Mendelian Rules (complex inheritance)

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Exceptions to Basic Mendelian Rules (complex inheritance)

Polygenic Traits When more than one gene contributes to the phenotype. Creates a wide range of phenotypes Examples – skin color, eye color, height

Incomplete Dominance dominant traits heterozygous red pink white In incomplete dominance, neither allele is __________ so there is a blending of ______ when two different alleles for the same trait occur together. Traits blend together (______________ individuals = 3rd phenotype) traits heterozygous red pink white

Incomplete Dominance RR WW RW In Four O’ Clocks, if you cross a red _____ (which is always pure) with a white _____ (that is also always pure) , you get a pink _____ (which is always hybrid / heterozygous WW RW RW RW RW RW

Incomplete Dominance RR BB RB In another flower, if red ____ and blue ____ flowers are crossed, they produce a 3rd purple ____ flower What would be the genotype ratio and phenotype ratio if you crossed two purple flowers? RB http://www.gwu.edu/~darwin/BiSc150/One/rose.GIF

Incomplete Dominance RB RB R B RR RB R red purple BB RB B purple blue Cross of two purple flowers ____ X ____ What are gamete possibilities? genotype ratio 1RR : 2RB : 1BB phenotype ratio 1red : 2 purple : 1 blue Can you have a heterozygous red or hybrid blue flower? ___ RB RB R B RR RB R red purple http://www.gwu.edu/~darwin/BiSc150/One/rose.GIF BB RB B purple blue no

Codominance Both _______ contribute to the phenotype of the organism by showing up simultaneously (at the same time) in heterozygous individuals. alleles In cattle and horses, if you cross a pure ____ (RR) with a pure ______ (WW), you get (RW) which produces the color _____. red white roan

Codominance phenotype R W RW WW W roan white RW WW W roan white These cattle or horses actually have both red and white hairs intermixed, or are spotted. Roan is a third ___________. If you cross a roan with a white… phenotype R W RW WW http://www.ccs.k12.in.us/chsteachers/Amayhew/Biology%20Notes/beyond%20dominance%20notes_files/image004.jpg W roan white RW WW W roan white

Codominance Andalusian chickens also show this pattern of inheritance. If you cross a black (BB) chicken With a white (WW) chicken You get black+white speckled (BW) chicken

Multiple Alleles two two two trait In this pattern of inheritance, the genes have more than _____ alleles controlling them and are therefore said to have multiple alleles. No individual has more than _____ alleles, but there are more than _____ possible alleles in a population, so a ______ will be expressed in more than two forms. two two two trait

Multiple Alleles Blood type in humans is an example of this inheritance pattern. The ______ different blood groups: A, B, O, and AB Are produced by ______ different alleles: A, B, and O Phenotype Genotype A AA or AO B BB or BO AB AB only O OO only four three

Multiple Alleles Examples of Blood type crosses

Multiple Alleles Blood Groups Antigen on Red Blood Cell Safe Transfusions Phenotype (Blood Type Genotype To From

Multiple Alleles rabbit The example of _______ hair color, which has at least four different alleles, (on text pg 273) is seen in these different Rex rabbits.

Sex Linked Traits Traits whose genes are found on the sex chromosomes (X or y) Traits will occur more frequently in one gender (ex- Hemophilia, a blood clotting disease whose gene is found on the X chromosome)

Practice 1 Let’s assume that dragons show incomplete dominance  for  fire  breathing.   The  F  allele  provides   lots  of  fire  and  the  F’  allele  gives  no  fire.    If  a dragon  that  has  very  strong  fire  is  crossed with  a  dragon  that  has  moderate  fire,  what  will   their offspring  be  like?   Under  what  conditions  can  a  baby dragon  be  born  that  never  has  fire?   Justify  your   answer  with  Punnett  Squares.   What type of dominance is this?

Practice 2 Let’s say that the color of merpeople’s tail is controlled  by  a  codominant  gene  and  the  alleles   are  blue  (B)  and  green  (G).    Show  a  cross  between  two  merpeople  who  have   bluish and green spotted  tails  (BG).    Give  the  offspring  phenotypes  with  percentages. What type of inheritance is this?