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Copyright © 2012 American Medical Association. All rights reserved. From: Comparison of Risk Prediction Using the CKD-EPI Equation and the MDRD Study Equation for Estimated Glomerular Filtration Rate JAMA. 2012;307(18):1941-1951. doi:10.1001/jama.2012.3954 Figure Legend: A, Distribution based on kernel density estimation (proportion is for each integer estimated glomerular filtration rate [GFR]). Dotted vertical lines define GFR categories used for chronic kidney disease staging. B-D, Error bars indicate 95% confidence intervals for estimated GFR by the CKD-EPI equation. Tinted bands indicate 95% confidence intervals for estimated GFR by the MDRD Study equation. Reference (open circle) is estimated GFR of 95 mL/min/1.73 m2. The filled circles (black and blue dots) represent statistical significance (P <.05). Adjustments were made for age, sex, race/ethnicity, smoking, history of cardiovascular disease, systolic blood pressure, diabetes, serum total cholesterol concentration, body mass index, and albuminuria. CKD-EPI indicates Chronic Kidney Disease Epidemiology Collaboration; MDRD, Modification of Diet in Renal Disease. Date of download: 1/23/2018 Copyright © 2012 American Medical Association. All rights reserved.

Copyright © 2012 American Medical Association. All rights reserved. From: Comparison of Risk Prediction Using the CKD-EPI Equation and the MDRD Study Equation for Estimated Glomerular Filtration Rate JAMA. 2012;307(18):1941-1951. doi:10.1001/jama.2012.3954 Figure Legend: Reclassification by the CKD-EPI equation in the general population cohorts. The blue and red bars indicate upward reclassification to a higher estimated GFR category and downward reclassification to a lower estimated GFR category, respectively. Data in pink and blue type are the number (percentage) of participants who were reclassified. Date of download: 1/23/2018 Copyright © 2012 American Medical Association. All rights reserved.

Copyright © 2012 American Medical Association. All rights reserved. From: Comparison of Risk Prediction Using the CKD-EPI Equation and the MDRD Study Equation for Estimated Glomerular Filtration Rate JAMA. 2012;307(18):1941-1951. doi:10.1001/jama.2012.3954 Figure Legend: The sizes of the data markers are proportional to the inverse of the variance of the NRIs. Date of download: 1/23/2018 Copyright © 2012 American Medical Association. All rights reserved.